Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive Lynch Syndrome patients

Walsh, M. D., Cummings, M. C., Buchanan, D. D., Dambacher, W. M., Arnold, S., McKeone, D., Byrnes, R., Barker, M. A., Leggett, B. A., Gattas, M., Jass, J. R., Spurdle, A. B., Young, J. and Obermair, A. (2008) Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive Lynch Syndrome patients. Clinical Cancer Research, 14 6: 1692-1700. doi:10.1158/1078-0432.CCR-07-1849


Author Walsh, M. D.
Cummings, M. C.
Buchanan, D. D.
Dambacher, W. M.
Arnold, S.
McKeone, D.
Byrnes, R.
Barker, M. A.
Leggett, B. A.
Gattas, M.
Jass, J. R.
Spurdle, A. B.
Young, J.
Obermair, A.
Title Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive Lynch Syndrome patients
Journal name Clinical Cancer Research   Check publisher's open access policy
ISSN 1078-0432
Publication date 2008-01-01
Year available 2008
Sub-type Article (original research)
DOI 10.1158/1078-0432.CCR-07-1849
Open Access Status
Volume 14
Issue 6
Start page 1692
End page 1700
Total pages 9
Editor Mendelsohn, J.
Place of publication Philadephia, U.S.A.
Publisher American Association for Cancer Research
Language eng
Subject C1
110316 Pathology (excl. Oral Pathology)
920102 Cancer and Related Disorders
Abstract Purpose: A woman with early-onset endometrial cancer (EC) may represent the "sentinel" cancer event in a Lynch syndrome kindred. The aim of this study was to determine the incidence of Lynch syndrome in a series of young-onset EC, and to identify molecular, clinical, and pathologic features that may alert clinicians to the presence of this disorder.
Keyword Oncology
Oncology
ONCOLOGY
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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Created: Tue, 24 Mar 2009, 21:31:23 EST by Brenda Mason on behalf of Molecular and Cellular Pathology - Sch of Med Cent