The use of placebo in clinical nursing research

Chan, Carmen W. H. and Thompson, David R. (2006) The use of placebo in clinical nursing research. Journal of Clinical Nursing, 15 5: 521-524. doi:10.1111/j.1365-2702.2006.01373.x

Author Chan, Carmen W. H.
Thompson, David R.
Title The use of placebo in clinical nursing research
Journal name Journal of Clinical Nursing   Check publisher's open access policy
ISSN 1365-2702
Publication date 2006-05-01
Sub-type Article (original research)
DOI 10.1111/j.1365-2702.2006.01373.x
Open Access Status Not yet assessed
Volume 15
Issue 5
Start page 521
End page 524
Total pages 4
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell
Language eng
Subject 1110 Nursing
Formatted abstract
Aims: This paper reviews placebo and placebo effects and their measurement and application to nursing. Ethical and methodological issues are also discussed. Implications for nursing and recommendations for future study are offered.

 Placebos have been used for decades in clinical trials but discussion about conceptual, methodological and ethical issues has been comparatively scarce.

It is concluded that true placebo effects are difficult to measure and control and the use of credible placebo is sometimes impractical in clinical nursing research. This leads to the increased use of usual care as a control by researchers. However, more information should be reported in studies that use this approach, including the specification of usual care, its monitoring and patient adherence.

Relevance to clinical practice:
Where its use is considered ethical, safe and feasible, a placebo arm should be included in studies of efficacy to distinguish between active and inactive treatment.
Keyword Placebo
Placebo effects
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Nursing, Midwifery and Social Work Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 6 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 24 Mar 2009, 00:03:17 EST by Ms Karen Naughton on behalf of School of Nursing, Midwifery and Social Work