“Compound blue nevus”: A reappraisal of “superficial blue nevus with prominent intraepidermal dendritic melanocytes” with emphasis on dermoscopic and histopathologic features

Ferrara, Gerardo, Argenziano, Giuseppe, Zgavec, Borut, Bartenjev, Igor, Staibano, Stefania, De Rosa, Gaetano and Soyer, H.Peter (2002) “Compound blue nevus”: A reappraisal of “superficial blue nevus with prominent intraepidermal dendritic melanocytes” with emphasis on dermoscopic and histopathologic features. Journal of the American Academy of Dermatology, 46 1: 85-89. doi:10.1067/mjd.2002.117858


Author Ferrara, Gerardo
Argenziano, Giuseppe
Zgavec, Borut
Bartenjev, Igor
Staibano, Stefania
De Rosa, Gaetano
Soyer, H.Peter
Title “Compound blue nevus”: A reappraisal of “superficial blue nevus with prominent intraepidermal dendritic melanocytes” with emphasis on dermoscopic and histopathologic features
Journal name Journal of the American Academy of Dermatology   Check publisher's open access policy
ISSN 0190-9622
Publication date 2002-01-01
Year available 2002
Sub-type Article (original research)
DOI 10.1067/mjd.2002.117858
Open Access Status Not yet assessed
Volume 46
Issue 1
Start page 85
End page 89
Total pages 5
Place of publication New York
Publisher Elsvier
Language eng
Subject 110304 Dermatology
Abstract We describe 5 cases of “compound blue nevus” (CBN) (“superficial blue nevus with prominent intraepidermal dendritic melanocytes,” “Kamino nevus”). Dermoscopically in 2 of 4 cases the bluish pigmentation characteristic of blue nevi was centrally replaced by a black lamella, with black dots and brown globules also observed in one case, thus revealing a structural asymmetry suggestive of melanoma. Histopathologically, pigmented parakeratosis was the underlying histopathologic finding of black lamella and dots/globules. Immunohistochemistry highlighted the unique histopathologic feature of CBN, namely, single dendritic melanocytes at the dermoepidermal junction with striking intraepidermal prolongations. Our findings confirm that CBN is a distinctive variant of blue nevus that may mimic cutaneous melanoma both clinically and dermoscopically. (J Am Acad Dermatol 2002;46:85-9.)
Keyword Dermatology
Dermatology
DERMATOLOGY
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
 
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