Fetomaternal cell trafficking and the stem cell debate : Gender matters

Bianchi, Diana W. and Fisk, Nicholas M. (2007) Fetomaternal cell trafficking and the stem cell debate : Gender matters. JAMA : The Journal of the American Medical Association, 297 13: 1489-1491. doi:10.1001/jama.297.13.1489

Author Bianchi, Diana W.
Fisk, Nicholas M.
Title Fetomaternal cell trafficking and the stem cell debate : Gender matters
Journal name JAMA : The Journal of the American Medical Association   Check publisher's open access policy
ISSN 0098-7484
Publication date 2007-04-04
Year available 2007
Sub-type Editorial
DOI 10.1001/jama.297.13.1489
Open Access Status
Volume 297
Issue 13
Start page 1489
End page 1491
Total pages 4
Place of publication Chicago Ill
Publisher AMA
Language eng
Subject 111401 Foetal Development and Medicine
111402 Obstetrics and Gynaecology
Abstract he current ethical, political, and scientific debates on stem cells pitch the benefits and limitations of 2 cell types against each other, adult vs embryonic stem cells. Embryonic stem cells derived from human blastocysts have the key advantage of pluripotency, meaning that they form nearly all cell types but also have the disadvantage of forming tumors in vivo, which may limit clinical application to tissue engineering rather than cell transplantation. In contrast, adult stem cells are derived from mature tissue, typically from bone marrow, but increasingly from most organs. In general, adult stem cells have low plasticity, although reports of differentiation outside traditional lineage boundaries suggest that some adult stem cells may be more pluripotent rather than multipotent.1 Aside from plasticity, these differing stem cell types have very different ethical issues
Keyword Stem cells
Q-Index Code CX
Q-Index Status Provisional Code
Grant ID G0300340
Institutional Status Unknown

Document type: Journal Article
Sub-type: Editorial
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 25 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 20 Mar 2009, 01:19:38 EST by Maryanne Watson on behalf of School of Medicine