Microalgae as bioreactors

Walker, Tara L., Purton, Saul, Becker, Douglas K. and Collet, Chris (2005) Microalgae as bioreactors. Plant Cell Reports, 24 11: 629-641. doi:10.1007/s00299-005-0004-6

Author Walker, Tara L.
Purton, Saul
Becker, Douglas K.
Collet, Chris
Title Microalgae as bioreactors
Journal name Plant Cell Reports   Check publisher's open access policy
ISSN 0721-7714
Publication date 2005-12-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s00299-005-0004-6
Open Access Status Not Open Access
Volume 24
Issue 11
Start page 629
End page 641
Total pages 13
Place of publication Heidelberg, Germany
Publisher Springer International
Language eng
Subject 0607 Plant Biology
Abstract Microalgae already serve as a major natural source of valuable macromolecules including carotenoids, long-chain polyunsaturated fatty acids and phycocolloids. As photoautotrophs, their simple growth requirements make these primitive plants potentially attractive bioreactor systems for the production of high-value heterologous proteins. The difficulty of producing stable transformants has meant that the field of transgenic microalgae is still in its infancy. Nonetheless, several species can now be routinely transformed and algal biotechnology companies have begun to explore the possibilities of synthesizing recombinant therapeutic proteins in microalgae and the engineering of metabolic pathways to produce increased levels of desirable compounds. In this review, we compare the current commercially viable bioreactor systems, outline recent progress in microalgal biotechnology and transformation, and discuss the potential of microalgae as bioreactors for the production of heterologous proteins.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
Queensland Brain Institute Publications
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Citation counts: TR Web of Science Citation Count  Cited 127 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 165 times in Scopus Article | Citations
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