Estimating the burden of disease attributable to diabetes in South Africa in 2000

Bradshaw, D., Norman, R., Pieterse, D. and Levitt, N. S. (2007) Estimating the burden of disease attributable to diabetes in South Africa in 2000. South African Medical Journal, 97 8 (Part 2): 700-706.

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Author Bradshaw, D.
Norman, R.
Pieterse, D.
Levitt, N. S.
Title Estimating the burden of disease attributable to diabetes in South Africa in 2000
Journal name South African Medical Journal   Check publisher's open access policy
ISSN 0038-2469
Publication date 2007-01-01
Sub-type Article (original research)
Open Access Status File (Publisher version)
Volume 97
Issue 8 (Part 2)
Start page 700
End page 706
Total pages 7
Place of publication Pinelands, South Africa
Publisher Medical Association of South Africa
Language eng
Subject 1117 Public Health and Health Services
Abstract Objectives. To estimate the burden of disease attributable to diabetes by sex and age group in South Africa in 2000. Design. The framework adopted for the most recent World Health Organization comparative risk assessment (CRA) methodology was followed. Small community studies used to derive the prevalence of diabetes by population group were weighted proportionately for a national estimate. Populationattributable fractions were calculated and applied to revised burden of disease estimates. Monte Carlo simulation-modelling techniques were used for uncertainty analysis. Setting. South Africa. Subjects. Adults 30 years and older. Outcome measures. Mortality and disability-adjusted life years (DALYs) for ischaemic heart disease (IHD), stroke, hypertensive disease and renal failure. Results. Of South Africans aged ≥ 30 years, 5.5% had diabetes which increased with age. Overall, about 14% of IHD, 10% of stroke, 12% of hypertensive disease and 12% of renal disease burden in adult males and females (30+ years) were attributable to diabetes. Diabetes was estimated to have caused 22 412 (95% uncertainty interval 20 755 - 24 872) or 4.3% (95% uncertainty interval 4.0 - 4.8%) of all deaths in South Africa in 2000. Since most of these occurred in middle or old age, the loss of healthy life years comprises a smaller proportion of the total 258 028 DALYs (95% uncertainty interval 236 856 - 290 849) in South Africa in 2000, accounting for 1.6% (95% uncertainty interval 1.5 - 1.8%) of the total burden. Conclusions. Diabetes is an important direct and indirect cause of burden in South Africa. Primary prevention of the disease through multi-level interventions and improved management at primary health care level are needed.
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Public Health Publications
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