Estimating the burden of disease attributable to alcohol use in South Africa in 2000

Schneider, Michelle, Norman, Rosana, Parry, Charles, Bradshaw, Debbie, Plüddemann, Andreas and South African Comparative Risk Assessment Collaborating Group (2007) Estimating the burden of disease attributable to alcohol use in South Africa in 2000. SAMJ South African Medical Journal, 97 8: 664-672.

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Name Description MIMEType Size Downloads
Author Schneider, Michelle
Norman, Rosana
Parry, Charles
Bradshaw, Debbie
Plüddemann, Andreas
South African Comparative Risk Assessment Collaborating Group
Title Estimating the burden of disease attributable to alcohol use in South Africa in 2000
Journal name SAMJ South African Medical Journal   Check publisher's open access policy
ISSN 0256-9574
Publication date 2007-08-01
Sub-type Article (original research)
Open Access Status File (Publisher version)
Volume 97
Issue 8
Start page 664
End page 672
Total pages 9
Place of publication Pinelands, Claremont, S.A.
Publisher Health and Medical Publishing Group
Language eng
Subject 1117 Public Health and Health Services
Formatted abstract
Objectives. To make quantitative estimates of the burden of disease attributable to alcohol use by sex and age group in South Africa in 2000.

Design. The analysis follows the World Health Organization comparative risk assessment (CRA) methodology. Population-attributable fractions (PAFs) calculated from modelled prevalence estimates and relative risks based on the global review were applied to the burden of disease estimates from the revised South African National Burden of Disease study for 2000. The alcohol-attributable fractions for injuries were directly determined from blood alcohol concentrations (BAC > 0.05 g/100 ml) at the time of injury. Monte Carlo simulation-modelling techniques were used to quantify uncertainty in the estimates.

Setting. South Africa.

Subjects. Adults ≥ 15 years.

Outcome measures. Deaths and disability-adjusted life years (DALYs) from ischaemic heart disease, stroke, hypertensive disease, diabetes, certain cancers, liver cirrhosis, epilepsy, alcohol use disorder, depression and intentional and unintentional injuries as well as burden from fetal alcohol syndrome (FAS) and low birth weight.

Results. Alcohol harm accounted for an estimated 7.1% (95% uncertainty interval 6.6 - 7.5%) of all deaths and 7.0% (95% uncertainty interval 6.6 - 7.4%) of total DALYs in 2000. Injuries and cardiovascular incidents ranked first and second in terms of attributable deaths. Top rankings for overall attributable burden were interpersonal violence (39.0%), neuropsychiatric conditions (18.4%) and road traffic injuries (14.3%). Interpersonal violence accounted for 42.8% of the injury DALYs attributed to alcohol in males and 25.9% in females. In terms of alcohol-attributable disability, alcohol use disorders ranked first (44.6%), interpersonal violence second (23.2%), and FAS third (18.1%).

Conclusions. Particular attention needs to be given to preventing and reducing the burden of alcohol-related homicide and violence, alcohol-related road traffic accidents, alcohol use disorders, and FAS. Multilevel interventions are required to target high-risk drinkers, in addition to creating awareness in the general population of the problems associated with alcohol abuse.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
ERA 2012 Admin Only
School of Public Health Publications
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Created: Mon, 02 Mar 2009, 22:01:25 EST by Juliette Grosvenor on behalf of School of Public Health