LOCATE: a mouse protein subcellular localization database

Fink, J. Lynn, Aturaliya, Rajith N., Davis, Melissa J., Zhang, Fasheng, Hanson, Kelly, Teasdale, Melvena S., Kai, Chikatoshi, Kawai, Jun, Carninci, Piero, Hayashizaki, Yoshihide and Teasdale, Rohan D. (2006) LOCATE: a mouse protein subcellular localization database. Nucleic Acids Research, 34 Supp. 1: D213-D217. doi:10.1093/nar/gkj069


Author Fink, J. Lynn
Aturaliya, Rajith N.
Davis, Melissa J.
Zhang, Fasheng
Hanson, Kelly
Teasdale, Melvena S.
Kai, Chikatoshi
Kawai, Jun
Carninci, Piero
Hayashizaki, Yoshihide
Teasdale, Rohan D.
Title LOCATE: a mouse protein subcellular localization database
Journal name Nucleic Acids Research   Check publisher's open access policy
ISSN 0305-1048
1362-4962
Publication date 2006-01-01
Year available 2005
Sub-type Article (original research)
DOI 10.1093/nar/gkj069
Open Access Status DOI
Volume 34
Issue Supp. 1
Start page D213
End page D217
Total pages 5
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Subject 060102 Bioinformatics
080604 Database Management
0601 Biochemistry and Cell Biology
0604 Genetics
1101 Medical Biochemistry and Metabolomics
Formatted abstract
We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for ∼40% of the mouse proteome. It is available at http://locate.imb.uq.edu.au
© The Author 2006. Published by Oxford University Press. All rights reserved.
Keyword Isoprotein
Membrane protein
Computer interface
Internet
Protein database
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Published in "Database Issue" (Supplement 1).

 
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