Universal interventions for the primary prevention of schizophrenia

McGrath, J (2000) Universal interventions for the primary prevention of schizophrenia. Ausralian and New Zealand Journal of Psychiatry, 34 Supplement: S58-S64. doi:10.1046/j.1440-1614.2000.00783.x

Author McGrath, J
Title Universal interventions for the primary prevention of schizophrenia
Journal name Ausralian and New Zealand Journal of Psychiatry   Check publisher's open access policy
ISSN 0004-8674
ISBN 978-1-4419-6295-9
Publication date 2000-01-01
Year available 2010
Sub-type Article (original research)
DOI 10.1046/j.1440-1614.2000.00783.x
Open Access Status
Volume 34
Issue Supplement
Start page S58
End page S64
Total pages 7
Editor Stanley V Catts
Brian I O'Toole and Daren M Draganic
Place of publication Carlton South, Vic
Publisher Blackwell Science
Language eng
Subject C1
Abstract Objective: To speculate on the role of universal (population-based) interventions designed to prevent schizophrenia. Method: A nonsystematic review of candidate risk factors for schizophrenia, with particular emphasis on the quality of the evidence, effect size of the risk factor, population attributable risk and potential for population-based intervention. Results: In order to design population-based interventions for the prevention of schizophrenia, we need to identify weak but prevalent risk factors. Based on current knowledge, the leading risk factors for schizophrenia include genes, season and place of birth, obstetric complications, prenatal exposure to viruses and prenatal nutrition. For the nongenetic exposures, we need to consider if potential interventions are effective, safe, cheap and acceptable. Conclusions: Vaccinations and interventions related to improving prenatal nutrition and antenatal care appear to be the most plausible options for universal prevention.
Keyword Psychiatry
Primary Prevention
Risk Factors
Universal Interventions
Bipolar Disorder
Q-Index Code C1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 10 Jun 2008, 22:05:02 EST