Expression of a Scr/Hox5 gene in the larval central nervous system of the gastropod Haliotis, a non-segmented spiralian lophotrochozoan

Giusti, A. F., Hinman, V. F., Degnan, S. M., Degnan, B. M and Morse, D. E. (2000) Expression of a Scr/Hox5 gene in the larval central nervous system of the gastropod Haliotis, a non-segmented spiralian lophotrochozoan. Evolution and Development, 2 5: 294-302. doi:10.1046/j.1525-142x.2000.00071.x


Author Giusti, A. F.
Hinman, V. F.
Degnan, S. M.
Degnan, B. M
Morse, D. E.
Title Expression of a Scr/Hox5 gene in the larval central nervous system of the gastropod Haliotis, a non-segmented spiralian lophotrochozoan
Journal name Evolution and Development   Check publisher's open access policy
ISSN 1520-541X
Publication date 2000-01-01
Sub-type Article (original research)
DOI 10.1046/j.1525-142x.2000.00071.x
Volume 2
Issue 5
Start page 294
End page 302
Total pages 9
Place of publication USA
Publisher Blackwell Science Ltd
Language eng
Subject C1
270502 Neurobiology
780105 Biological sciences
Abstract Hox genes encode a set of evolutionarily conserved transcription factors that regulate anteroposterior patterning mechanisms in insects and vertebrates and are expressed along this axis in a range of bilaterians. Here we present the developmental expression of a Scr/Hox5 gene in the gastropod mollusc Haliotis. In Haliotis, embryogenesis yields a non-feeding trochophore larva that subsequently develops into the veliger larva, which possesses many of the characteristics of the adult body plan. Quantitative RT-PCR analysis reveals that this gene, which is called Hru-Hox5, is first expressed in the trochophore larva. Hru-Hox5 transcript prevalence increases continually through larval development until metamorphic competence develops in the veliger and then again over the first four days of metamorphosis. In situ hybridization reveals that larval expression of Hru-Hox5 is restricted primarily to the primordial and newly formed branchial ganglia, located between the anterior cerebral-pleuropedal ganglionic complex and the posterior visceral ganglia. The expression of Hru-Hox5 in the central region of the abalone CNS is similar to that observed for its orthologue (Lox20) in the leech, suggesting that Hox5 genes were used, along with other Hox genes, to pattern the CNS of the ancestral spiralian lophotrochozoan.
Keyword Evolutionary Biology
Developmental Biology
Genetics & Heredity
Messenger-rna Expression
Homeobox Genes
Hox Genes
Leech Helobdella
Rt-pcr
Metamorphosis
Evolution
Rufescens
Patterns
Regionalization
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Biological Sciences Publications
 
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Created: Tue, 10 Jun 2008, 21:42:07 EST