The prevalence of human thymic lymphoid follicles is lower in suicides

Middleton, G. and Schoch, E. M. (2000) The prevalence of human thymic lymphoid follicles is lower in suicides. Virchows Archiv, 436 2: 127-130. doi:10.1007/PL00008211


Author Middleton, G.
Schoch, E. M.
Title The prevalence of human thymic lymphoid follicles is lower in suicides
Journal name Virchows Archiv   Check publisher's open access policy
ISSN 0945-6317
Publication date 2000-01-01
Sub-type Article (original research)
DOI 10.1007/PL00008211
Volume 436
Issue 2
Start page 127
End page 130
Total pages 4
Place of publication Berlin
Publisher Springer-Verlag
Language eng
Subject C1
321020 Pathology
730102 Immune system and allergy
Abstract In an autopsy study we determined the prevalence of thymic lymphoid follicles in 311 accident victims in whom the time interval between accident and death was known. We found that the prevalence decreased abruptly in those surviving 48 h or more (P=0.000008). We then compared the prevalence in 271 accident and 168 suicide victims, all of whom had died less than 48 h after the incident and found that the prevalence was significantly lower in the suicide group (P=0.03). We conclude that this difference may be related to the effect on the thymus of high levels of psychological stress likely to have been experienced by the suicides in the days prior to the act. The use of the term hyperplasia to indicate the presence of lymphoid follicles in the thymus and the methodology appropriate for determining the prevalence of thymic lymphoid follicles are discussed.
Keyword Pathology
Human Thymus
Lymphoid Follicles
Suicide
Accidental Death
Psychological Stress
Thymic Hyperplasia
Stress
Neuroendocrine
Modulation
Mechanisms
Involution
Immunity
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 10 Jun 2008, 20:31:29 EST