Effect of a static magnetic field on orthodontic tooth movement in the rat

Tengku, B. S., Joseph, B. K., Harbrow, D., Taverne, A. A. R. and Symons, A. L. (2000) Effect of a static magnetic field on orthodontic tooth movement in the rat. European Journal of Orthodontics, 22 5: 475-487. doi:10.1093/ejo/22.5.475


Author Tengku, B. S.
Joseph, B. K.
Harbrow, D.
Taverne, A. A. R.
Symons, A. L.
Title Effect of a static magnetic field on orthodontic tooth movement in the rat
Journal name European Journal of Orthodontics   Check publisher's open access policy
ISSN 0141-5387
Publication date 2000-01-01
Sub-type Article (original research)
DOI 10.1093/ejo/22.5.475
Volume 22
Issue 5
Start page 475
End page 487
Total pages 13
Place of publication Oxford, UK
Publisher Oxford Univ Press
Language eng
Subject C1
320899 Dentistry not elsewhere classified
730112 Oro-dental and disorders
Abstract Orthodontic tooth movement may be enhanced by the application of a magnetic field. Bone remodelling necessary for othodontic tooth movement involves elastic cells, which are tartrate-resistant acid phosphatase (TRAP) positive and which may also be regulated by growth hormone (GH) via its receptor (GHR). The aim of this study was to determine the effect of a static magnetic field (SMF) on orthodontic tooth movement in the rat. Thirty-two male Wistar rats, 9 weeks old, were fitted with an orthodontic appliance directing a mesial force of 30 g on the left maxillary first molar. The appliance incorporated a weight (NM) or a magnet (M). The animals were killed at 1, 3, 7, or 14 days post-appliance insertion, and the maxillae processed to paraffiin. Sagittal sections of the first molar were stained with haematoxylin and eosin (H&E), for TRAP activity or immunohistochemically for GHR. The percentage body weight loss/gain, magnetic flux density, tooth movement, width of the periodontal ligament (PDL), length of root resorption lacunae, and hyalinized zone were measured. TRAP and GHR-positive cells along the alveolar bone, root surface, and in the PDL space were counted. The incorporation of a SMF (100-170 Gauss) into an orthodontic appliance did not enhance tooth movement, nor greatly alter the histological appearance of the PDL during tooth movement. However significantly greater root resorption (P = 0.016), increased width of the PDL (P= 0.017) and greater TRAP activity (P= 0.001) were observed for group M at day 7 on the compression side. At day 14 no differences were observed between the appliance groups.
Keyword Dentistry, Oral Surgery & Medicine
Pulsed Electromagnetic-fields
Growth-hormone Receptor
Dna-synthesis
Factor-i
Bone
Invitro
Expression
Cells
Fibroblasts
Binding
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
 
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Created: Tue, 10 Jun 2008, 20:26:55 EST