Pathways to ecstasy use in young adults: Anxiety, depression or behavioural deviance?

Alati, Rosa, Kinner, Stuart, Hayatbakhsh, Mohammad, Mamun, Abdullah, Najman, Jake and Williams, Gail (2008) Pathways to ecstasy use in young adults: Anxiety, depression or behavioural deviance?. Drug and Alcohol Dependence, 92 1-3: 108-115. doi:10.1016/j.drugalcdep.2007.07.007

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Author Alati, Rosa
Kinner, Stuart
Hayatbakhsh, Mohammad
Mamun, Abdullah
Najman, Jake
Williams, Gail
Title Pathways to ecstasy use in young adults: Anxiety, depression or behavioural deviance?
Journal name Drug and Alcohol Dependence   Check publisher's open access policy
ISSN 0376-8716
Publication date 2008-01-01
Year available 2007
Sub-type Article (original research)
DOI 10.1016/j.drugalcdep.2007.07.007
Open Access Status File (Author Post-print)
Volume 92
Issue 1-3
Start page 108
End page 115
Total pages 8
Place of publication Switzerland
Publisher Elsevier
Language eng
Subject 1103 Clinical Sciences
Formatted abstract
Aims: To investigate pathways to ecstasy use disorders from pre-birth to early adulthood with particular attention to the relationship between early depressive and anxiety symptoms and later ecstasy use disorders.

Design: Prospective, longitudinal, population-based study started in Brisbane, South East Queensland (Australia) in 1981. Participants were 2143 young adults, followed up from pre-birth to young adulthood.

Measurements: Ecstasy use disorders were assessed with the composite international diagnostic interview (CIDI-Auto). Maternal socio-economic position and mental health status were assessed at baseline (antenatal visit); maternal substance use was measured at the 5-year follow-up, adolescents’ behaviour at the 5- and 14-year follow-up and tobacco and alcohol use were assessed at the 14-year follow-up.

Findings: Eight syndrome scales of childhood behaviour were examined. After adjustment for important confounders, delinquent and aggressive behaviour in early adolescence remained significantly associated with ecstasy use disorders in early adulthood. The associations became statistically non-significant when adolescent tobacco and alcohol use were included in the model [OR = 1.50 (95%CI = 0.75, 3.01) for delinquency and OR = 1.69 (95%CI = 0.92, 3.12) for aggression]. Formal mediation tests were statistically significant (p = 0.001 for delinquent behaviour and p = 0.05 for aggressive behaviour).

Our findings suggest a pathway from early deviant behaviour to ecstasy use disorders, possibly mediated through licit drug experimentation in early adolescence.
Keyword Ecstasy use disorders
Delinquent and aggressive behaviour
Early depressive and anxiety symptoms
Drug experimentation
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2008 Higher Education Research Data Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 22 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 23 times in Scopus Article | Citations
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Created: Sat, 29 Mar 2008, 02:37:45 EST