Mechanoreceptive and nociceptive responses in the central nervous system of goldfish (Carassius auratus) and trout (Oncorhynchus mykiss)

Dunlop, R. and Laming, P. (2005) Mechanoreceptive and nociceptive responses in the central nervous system of goldfish (Carassius auratus) and trout (Oncorhynchus mykiss). Journal of Pain, 6 9: 561-568. doi:10.1016/j.jpain.2005.02.010


Author Dunlop, R.
Laming, P.
Title Mechanoreceptive and nociceptive responses in the central nervous system of goldfish (Carassius auratus) and trout (Oncorhynchus mykiss)
Journal name Journal of Pain   Check publisher's open access policy
ISSN 1526-5900
Publication date 2005-09-01
Sub-type Article (original research)
DOI 10.1016/j.jpain.2005.02.010
Volume 6
Issue 9
Start page 561
End page 568
Total pages 8
Place of publication Edinburgh
Publisher Churchill Livingstone
Language eng
Abstract Nociceptive responses to a repetitive pin-prod stimulus in goldfish and trout were assessed. Single unit recordings were taken from the spinal cord, cerebellum, tectum, and telencephalon. Neuronal responses were elicited in all these regions of the central nervous system in both species of fish during brush (mechanoceptive) and pin-prod (nociceptive) stimuli. In addition, in trout, a heated prod stimulus was used. Mechanoreceptive and nociceptive neuronal responses to various stimuli were elicited in all regions, and responses were detected as far as the telencephalon in both species. In goldfish, a noxious stimulus produced greater neuronal activity than a mechanoreceptive stimulus. This was not found in trout. The accurate setting of timed prods allowed the latency of the response to be calculated in all regions. From these data, conduction velocities suggested that A delta and C fibers were activated; both fiber groups previously have been shown to be involved in nociception in fish. This study has shown that there is neuronal activity in all brain areas including the telencephalon, suggesting a nociceptive pathway from the periphery to the higher central nervous system of fish. Perspective: This study presents novel data on teiencephalic activity in fish after noxious stimulation and demonstrates the potential for pain perception in lower vertebrates. Not only is this of an evolutionary significance, but it also adds to the controversial argument about whether fish perceive pain. (c) 2005 by the American Pain Society.
Keyword Clinical Neurology
Neurosciences
nociception
mechanoreception
pain
fish
Teleost Fish
Skin
Pain
Telencephalon
Evolution
Fibers
Q-Index Code C1

 
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Created: Sat, 29 Mar 2008, 01:31:01 EST