Geographic variation and positive selection on M7 lysin, an acrosomal sperm protein in mussels (Mytilus spp.)

Riginos, Cynthia, Wang, Duane and Abrams, A. Jeanine (2006) Geographic variation and positive selection on M7 lysin, an acrosomal sperm protein in mussels (Mytilus spp.). Molecular Biology and Evolution, 23 10: 1952-1965. doi:10.1093/molbev/msl062

Author Riginos, Cynthia
Wang, Duane
Abrams, A. Jeanine
Title Geographic variation and positive selection on M7 lysin, an acrosomal sperm protein in mussels (Mytilus spp.)
Journal name Molecular Biology and Evolution   Check publisher's open access policy
ISSN 0737-4038
Publication date 2006-01-01
Sub-type Article (original research)
DOI 10.1093/molbev/msl062
Open Access Status
Volume 23
Issue 10
Start page 1952
End page 1965
Total pages 14
Place of publication Oxford, UK
Publisher Oxford University Press
Language eng
Subject 270000 Biological Sciences
270700 Ecology and Evolution
270200 Genetics
0604 Genetics
Abstract Successful fertilization in free-spawning marine organisms depends on the interactions between genes expressed on the surfaces of eggs and sperm. Positive selection frequently characterizes the molecular evolution of such genes, raising the possibility that some common deterministic process drives the evolution of gamete recognition genes and may even be important for understanding the evolution of prezygotic isolation and speciation in the marine realm. One hypothesis is that gamete recognition genes are subject to selection for prezygotic isolation, namely reinforcement. In a previous study, positive selection on the gene coding for the acrosomal sperm protein M7 lysin was demonstrated among allopatric populations of mussels in the Mytilus edulis species group (M. edulis, M. galloprovincialis, and M. trossulus). Here, we expand sampling to include M7 lysin haplotypes from populations where mussel species are sympatric and hybridize to determine whether there is a pattern of reproductive character displacement, which would be consistent with reinforcement driving selection on this gene. We do not detect a strong pattern of reproductive character displacement; there are no unique haplotypes in sympatry nor is there consistently greater population structure in comparisons involving sympatric populations. One distinct group of haplotypes, however, is strongly affected by natural selection and this group of haplotypes is found within M. galloprovincialis populations throughout the Northern Hemisphere concurrent with haplotypes common to M. galloprovincialis and M. edulis. We suggest that balancing selection, perhaps resulting from sexual conflicts between sperm and eggs, maintains old allelic diversity within M. galloprovincialis.
Keyword Biochemistry & Molecular Biology
Evolutionary Biology
Genetics & Heredity
balancing selection
gamete recognition
reproductive character displacement
reproductive isolation
Tropical Sea-urchins
Vitelline Envelope Receptor
Codon-substitution Models
Edulis Species Complex
Amino-acid Sites
Sexual Conflict
Reproductive Proteins
Darwinian Selection
Gamete Recognition
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Biological Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 42 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 42 times in Scopus Article | Citations
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Created: Thu, 29 Mar 2007, 01:07:21 EST by Dr Cynthia Riginos on behalf of School of Biological Sciences