Herbal medicines in the treatment of psychiatric disorders: A systematic review

Sarris, J. (2007) Herbal medicines in the treatment of psychiatric disorders: A systematic review. Phytotherapy Research, 21 8: 703-716. doi:10.1002/ptr.2187

Author Sarris, J.
Title Herbal medicines in the treatment of psychiatric disorders: A systematic review
Journal name Phytotherapy Research   Check publisher's open access policy
ISSN 0951-418X
Publication date 2007-06-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/ptr.2187
Open Access Status DOI
Volume 21
Issue 8
Start page 703
End page 716
Total pages 14
Editor E. M. Williamson
Place of publication Chichester, U.K.
Publisher John Wiley & Sons
Language eng
Subject 321021 Psychiatry
730211 Mental health
Abstract This paper reports a critical review of 27 herbal medicines and formulas in treating a broad range of psychiatric disorders (in addition to anxiety and depression), including obsessive-compulsive, seasonal affective, bipolar depressive, psychotic, phobic and somatoform disorders. Ovid Medline, Pubmed and the Cochrane Library were searched for pharmacological and clinical evidence of herbal medicines with psychotropic activity. A forward search of later citations was also conducted. Whilst substantial high-quality evidence exists for the use of kava and St John's wort in the treatment of anxiety and depression respectively, currently there is insufficient robust clinical evidence for the use of many other herbal medicines in psychiatric disorders. Phytotherapies which potentially have significant use in psychiatry, and urgently require more research are Rhodiola rosea (roseroot) and Crocus sativus (saffron) for depression; Passiflora incarnata (passionflower), Scutellaria lateriflora (scullcap) and Zizyphus jujuba (sour date) for anxiety disorders; and Piper methysticum (kava) for phobic, panic and obsessive-compulsive disorders. While depression and anxiety are commonly researched, the efficacy of herbal medicines in other mental disorders requires attention. The review addresses current issues in herbal psychotherapy: herbal safety, future areas of application, the relationship of herbal medicine with pharmaceuticals and the potential prescriptive integration of phytomedicines with synthetic psychotropic medicines. Particular attention is given to clinical and safety issues with St John's wort and kava. Copyright © 2007 John Wiley & Sons, Ltd.
Keyword Chemistry, Medicinal
Pharmacology & Pharmacy
herbal medicine
complementary medicine
medicinal plants
mood disorders
psychiatric disorders
Generalized Anxiety Disorder
To-moderate Depression
Placebo-controlled Trial
Randomized Controlled-trial
Crocus-sativus L.
Seasonal Affective-disorder
Laboratory-induced Stress
Officinalis Lemon Balm
Banxia Houpu Decoction
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
2008 Higher Education Research Data Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 72 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 91 times in Scopus Article | Citations
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Created: Mon, 17 Mar 2008, 17:58:35 EST by Brenda Mason on behalf of Psychiatry - Royal Brisbane and Women's Hospital