Association of APOE with Parkinson disease age-at-onset in women

Buchanan, Daniel D., Silburn, Peter A., Prince, Jonathan A. and Mellick, George D. (2007) Association of APOE with Parkinson disease age-at-onset in women. Neuroscience Letters, 411 3: 185-188. doi:10.1016/j.neulet.2006.07.080

Author Buchanan, Daniel D.
Silburn, Peter A.
Prince, Jonathan A.
Mellick, George D.
Title Association of APOE with Parkinson disease age-at-onset in women
Journal name Neuroscience Letters   Check publisher's open access policy
ISSN 0304-3940
Publication date 2007-01-16
Sub-type Article (original research)
DOI 10.1016/j.neulet.2006.07.080
Open Access Status
Volume 411
Issue 3
Start page 185
End page 188
Total pages 4
Editor S. G. Waxman
Place of publication Shannon, Co. Clare Ireland
Publisher Elsevier Ireland
Language eng
Subject 1109 Neurosciences
Formatted abstract
APOE polymorphism has received extensive attention as a risk factor for Parkinson's disease (PD), but findings have been equivocal. Analysis of APOE variants in an Australian PD case–control sample revealed a robust association between genotype and age-at-onset (AAO) of PD in women (P = 0.0008). These data not only further implicate APOE in PD, but also provide a stark example of the effects that gender may play in complex disorders.
Keyword Neurosciences
Parkinson's disease
Genetic association studies
Q-Index Code C1
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Journal Article Import (ISI/CVs)
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 19 Feb 2008, 02:15:55 EST