rRNA genes from the lower chordate Herdmania momus; structural similarity with higher eukaryotes.

Degnan, B. M., Yan, J., Hawkins, C. J. and Lavin, M. F. (1990) rRNA genes from the lower chordate Herdmania momus; structural similarity with higher eukaryotes.. Nucleic Acids Research, 18 23: 7063-7070. doi:10.1093/nar/18.23.7063


Author Degnan, B. M.
Yan, J.
Hawkins, C. J.
Lavin, M. F.
Title rRNA genes from the lower chordate Herdmania momus; structural similarity with higher eukaryotes.
Journal name Nucleic Acids Research   Check publisher's open access policy
ISSN 0305-1048
Publication date 1990-12-11
Sub-type Article (original research)
DOI 10.1093/nar/18.23.7063
Open Access Status DOI
Volume 18
Issue 23
Start page 7063
End page 7070
Total pages 8
Place of publication Oxford
Publisher Oxford University Press
Language eng
Subject 270504 Invertebrate Biology
270200 Genetics
Abstract Ascidians, primitive chordates that have retained features of the likely progenitors to all vertebrates, are a useful model to study the evolutionary relationship of chordates to other animals. We have selected the well characterized ribosomal RNA (rRNA) genes to investigate this relationship, and we describe here the cloning and characterization of an entire ribosomal DNA (rDNA) tandem repeat unit from a lower chordate, the ascidian Herdmania momus. rDNA copy number and considerable sequence differences were observed between two H. momus populations. Comparison of rDNA primary sequence and rRNA secondary structures from H. momus with those from other well characterized organisms, demonstrated that the ascidians are more closely related to other chordates than invertebrates. The rDNA tandem repeat makes up a larger percentage (7%) of the genome of this animal than in other higher eukaryotes. The total length of the spacer and transcribed region in H. momus rDNA is small compared to most higher eukaryotes, being less than 8 kb, and the intergenic spacer region consists of smaller internal repeats. Comparative analysis of rDNA sequences has allowed the construction of secondary structures for the 18S, 5.8S and 26S rRNAs.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Degnan Laboratory
UQ Centre for Clinical Research Publications
School of Biological Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 21 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 20 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 06 Dec 2007, 02:28:39 EST by Laura McTaggart on behalf of UQ Centre for Clinical Research