Mapping postnatal mouse brain development with diffusion tensor microimaging

Zhang, J. Y., Miller, M. I., Plachez, C., Richards, L. J., Yarowsky, P., van Zijl, P. and Mori, S. (2005) Mapping postnatal mouse brain development with diffusion tensor microimaging. Neuroimage, 26 4: 1042-1051. doi:10.1016/j.neuroimage.2005.03.009

Author Zhang, J. Y.
Miller, M. I.
Plachez, C.
Richards, L. J.
Yarowsky, P.
van Zijl, P.
Mori, S.
Title Mapping postnatal mouse brain development with diffusion tensor microimaging
Journal name Neuroimage   Check publisher's open access policy
ISSN 1053-8119
Publication date 2005-01-01
Year available 2005
Sub-type Article (original research)
DOI 10.1016/j.neuroimage.2005.03.009
Open Access Status
Volume 26
Issue 4
Start page 1042
End page 1051
Total pages 10
Place of publication San Diego
Publisher Academic Press Inc Elsevier Science
Language eng
Abstract While mouse brain development has been extensively studied using histology, quantitative characterization of morphological changes is still a challenging task. This paper presents how developing brain structures can be quantitatively characterized with magnetic resonance diffusion tensor microimaging coupled with techniques of computational anatomy. High resolution diffusion tensor images of ex vivo postnatal mouse brains provide excellent contrasts to reveal the evolutions of mouse forebrain structures. Using anatomical landmarks defined on diffusion tensor images, tissue level growth patterns of mouse brains were quantified. The results demonstrate the use of these techniques to three-dimensionally and quantitatively characterize brain growth. (c) 2005 Elsevier Inc. All rights reserved.
Keyword Neurosciences
Radiology, Nuclear Medicine & Medical Imaging
mouse brain development
diffusion tensor
computational neuroanatomy
Gray-matter Loss
Computational Anatomy
Q-Index Code C1
Grant ID P41 RR 15241-01
R01 AG 20012-01
P41 EB015909
R03 HD 41407-01A1
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Biomedical Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 57 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 20 Sep 2007, 03:10:01 EST