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Medeiros, Rodrigo, Castello, Nicholas A., Cheng, David, Kitazawa, Masashi, Baglietto-Vargas, David, Green, Kim N., Esbenshade, Timothy A., Bitner, Robert S., Decker, Michael W. and LaFerla, Frank M. (2014) α7 nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. American Journal of Pathology, 184 2: 520-529. doi:10.1016/j.ajpath.2013.10.010     31 Cited 32 times in Scopus32 1
Fisher, Abraham, Bezprozvanny, Ilya , Wu, Lili, Ryskamp, Daniel A., Bar-Ner, Nira, Natan, Niva, Brandeis, Rachel , Elkon, Hanoch, Nahum, Victoria , Gershonov, Eitan, LaFerla, Frank M. and Medeiros, Rodrigo (2016) AF710B, a novel M1/σ1 agonist with therapeutic efficacy in animal models of Alzheimer's disease. Neurodegenerative Diseases, 16 1-2: 95-110. doi:10.1159/000440864     10 Cited 11 times in Scopus11 11
Clarke, Julia R., Lyra E Silva, Natalia M., Figueiredo, Claudia P., Frozza, Rudimar L., Ledo, Jose H., Beckman, Danielle, Katashima, Carlos K., Razolli, Daniela, Carvalho, Bruno M., Frazão, Renata, Silveira, Marina A., Ribeiro, Felipe C., Bomfim, Theresa R., Neves, Fernanda S., Klein, William L., Medeiros, Rodrigo, LaFerla, Frank M., Carvalheira, Jose B., Saad, Mario J., Munoz, Douglas P., Velloso, Licio A., Ferreira, Sergio T. and De Felice, Fernanda G. (2015) Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Molecular Medicine, 7 2: 190-210. doi:10.15252/emmm.201404183     67 Cited 69 times in Scopus69 8
Medeiros, Rodrigo, Kitazawa, Masashi, Passos, Giselle F., Baglietto-Vargas, David, Cheng, David, Cribbs, David H. and LaFerla, Frank M. (2013) Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces alzheimer disease-like pathology in mice. The American Journal of Pathology, 182 5: 1780-1789. doi:10.1016/j.ajpath.2013.01.051     57 Cited 65 times in Scopus65 1
Medeiros, Rodrigo and LaFerla, Frank M. (2013) Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony. Experimental Neurology, 239 1: 133-138. doi:10.1016/j.expneurol.2012.10.007     88 Cited 89 times in Scopus89 1
Bicca, M. A., Costa, R., Loch-Neckel, G., Figueiredo, C. P., Medeiros, R. and Calixto, J. B. (2015) B2 receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition. Behavioural Brain Research, 278 482-491. doi:10.1016/j.bbr.2014.10.040     9 Cited 10 times in Scopus10
Bitencourt, Rafael M., Guerra de Souza, Ana C., Bicca, Maíra A., Pamplona, Fabrício A., de Mello, Nelson, Passos, Giselle F., Medeiros, Rodrigo, Takahashi, Reinaldo N., Calixto, João B. and Prediger, Rui D. (2017) Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats. Behavioural Brain Research, 316 74-81. doi:10.1016/j.bbr.2016.08.041     1 Cited 1 times in Scopus1
Medeiros, R., Kitazawa, M., Chabrier, M. A., Cheng, D., Baglietto-Vargas, D., Kling, A., Moeller, A., Green, K. N. and LaFerla, F. M. (2012) Calpain Inhibitor A-705253 Mitigates Alzheimer's Disease-Like Pathology and Cognitive Decline in Aged 3xTg-AD Mice. American Journal of Pathology, 181 2: 616-625. doi:10.1016/j.ajpath.2012.04.020     47 Cited 53 times in Scopus53 6
Zumkehr, Joannee, Rodriguez-Ortiz, Carlos J., Cheng, David, Kieu, Zanett, Wai, Thin, Hawkins, Charlesice, Kilian, Jason, Lim, Siok Lam, Medeiros, Rodrigo and Kitazawa, Masashi (2015) Ceftriaxone ameliorates tau pathology and cognitive decline via restoration of glial glutamate transporter in a mouse model of Alzheimer's disease. Neurobiology of Aging, 36 7: 2260-2271. doi:10.1016/j.neurobiolaging.2015.04.005     38 Cited 42 times in Scopus42 12
Dagher, Nabil N., Najafi, Allison R., Kayala, Kara M. Neely, Elmore, Monica R. P., White, Terra E., Medeiros, Rodrigo, West, Brian L. and Green, Kim N. (2015) Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice. Journal of Neuroinflammation, 12 . doi:10.1186/s12974-015-0366-9     72 Cited 73 times in Scopus73 10
Kitazawa, Masashi, Hsu, Heng-Wei and Medeiros, Rodrigo (2016) Copper exposure perturbs brain inflammatory responses and impairs clearance of amyloid-beta. Toxicological Sciences, 152 1: 194-204. doi:10.1093/toxsci/kfw081     9 Cited 9 times in Scopus9 11
Forner, Stefania, Andrade, Edineia L., Martini, Alessandra C., Bento, Allisson F., Medeiros, Rodrigo, Koepp, Janice and Calixto, Joao B. (2012) Effects of kinin B1 and B2 receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats. British Journal of Pharmacology, 167 8: 1737-1752. doi:10.1111/j.1476-5381.2012.02127.x     11 Cited 11 times in Scopus11 1
Medeiros, Rodrigo, Chabrier, Meredith A. and LaFerla, Frank M. (2017) Elucidating the triggers, progression, and effects of Alzheimer's disease. Journal of Alzheimers Disease, 33 SUPPL. 1: S195-S210. doi:10.3233/JAD-2012-129009     19 Cited 18 times in Scopus18 0
Baglietto-Vargas, David, Kitazawa, Masashi, Le, Elaine J., Estrada-Hernandez, Tatiana, Rodriguez-Ortiz, Carlos J., Medeiros, Rodrigo, Green, Kim N. and LaFerla, Frank M. (2014) Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition. Neurobiology of Disease, 62 407-415. doi:10.1016/j.nbd.2013.10.019     14 Cited 14 times in Scopus14 0
Basei, Fernanda L., Cabrini, Daniela A., Figueiredo, Claudia P., Forner, Stefania, Hara, Daniela B., Nascimento, Andrey F. Z., Ceravolo, Graziela S., Carvalho, Maria Helena C., Bader, Michael, Medeiros, Rodrigo and Calixto, Joao B. (2012) Endothelium dependent expression and underlying mechanisms of des-Arg 9-bradykinin-induced B1R-mediated vasoconstriction in rat portal vein. Peptides, 37 2: 216-224. doi:10.1016/j.peptides.2012.07.020     5 Cited 5 times in Scopus5 0
Figueiredo, Claudia P., Bicca, Maria A., Latini, Alexandra, Prediger, Rui Daniel S., Medeiros, Rodrigo and Calixto, Joao B. (2011) Folic acid plus α-tocopherol mitigates amyloid-β-induced neurotoxicity through modulation of mitochondrial complexes activity. Journal of Alzheimers Disease, 24 1: 61-75. doi:10.3233/JAD-2010-101320     22 Cited 23 times in Scopus23 0
Abbondante, Serena, Baglietto-Vargas, David, Rodriguez-Ortiz, Carlos J., Estrada-Hernandez, Tatiana, Medeiros, Rodrigo and LaFerla, Frank M. (2014) Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes. American Journal of Pathology, 184 3: 819-826. doi:10.1016/j.ajpath.2013.11.021     20 Cited 20 times in Scopus20 0
Figueiredo, Claudia P., Antunes, Victor L. S., Moreira, Eduardo L. G., de Mello, Nelson, Medeiros, Rodrigo, Di Giunta, Gabriella, Lobao-Soares, Bruno, Linhares, Marcelo, Lin, Katia, Mazzuco, Tania L., Prediger, Rui D. S. and Walz, Roger (2011) Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus. Peptides, 32 4: 781-789. doi:10.1016/j.peptides.2010.12.010     10 Cited 11 times in Scopus11 0
Baglietto-Vargas, David, Prieto, Gilberto Aleph, Limon, Agenor, Forner, Stefania, Rodriguez-Ortiz, Carlos J., Ikemura, Kenji, Ager, Rahasson R., Medeiros, Rodrigo, Trujillo-Estrada, Laura, Martini, Alessandra C., Kitazawa, Masashi, Davila, Jose C., Cotman, Carl W., Gutierrez, Antonia and LaFerla, Frank M (2018) Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell, . doi:10.1111/acel.12791     0 Cited 2 times in Scopus2 6
Sy, Michael, Kitazawa, Masashi, Medeiros, Rodrigo, Whitman, Lucia, Cheng, David, Lane, Thomas E. and LaFerla, Frank M. (2011) Inflammation induced by infection potentiates tau pathological features in transgenic mice. American Journal of Pathology, 178 6: 2811-2822. doi:10.1016/j.ajpath.2011.02.012     82 Cited 86 times in Scopus86 0
Newcombe, Estella A., Camats-Perna, Judith, Silva, Mallone L., Valmas, Nicholas, Huat, Tee Jong and Medeiros, Rodrigo (2018) Inflammation: the link between comorbidities, genetics, and Alzheimer's disease. Journal of Neuroinflammation, 15 . doi:10.1186/s12974-018-1313-3     1 Cited 1 times in Scopus1 25
Zumkehr, Joannee, Rodriguez-Ortiz, Carlos J, Medeiros, Rodrigo and Kitazawa, Masashi (2018) Inflammatory cytokine, IL-1β, regulates glial glutamate transporter via microRNA-181a in vitro. Journal of Alzheimer's Disease, 63 3: 965-975. doi:10.3233/JAD-170828     1 Cited 1 times in Scopus1 1
Medeiros, Rodrigo, Kitazawa, Masashi, Caccamo, Antonella, Baglietto-Vargas, David, Estrada-Hernandez, Tatiana, Cribbs, David H., Fisher, Avraham and LaFerla, Frank M. (2011) Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline. American Journal of Pathology, 179 2: 980-991. doi:10.1016/j.ajpath.2011.04.041     55 Cited 55 times in Scopus55
Baglietto-Vargas, David, Medeiros, Rodrigo, Martinez-Coria, Hilda, LaFerla, Frank M. and Green, KN (2013) Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology. Biological Psychiatry, 74 5: 357-366. doi:10.1016/j.biopsych.2012.12.003     41 Cited 43 times in Scopus43 1
Walls, Ken C., Ager, Rahasson R., Vasilevko, Vitaly, Cheng, Dave, Medeiros, Rodrigo and LaFerla, Frank M. (2014) P-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice. Neuroscience Letters, 575 96-100. doi:10.1016/j.neulet.2014.05.047     30 Cited 30 times in Scopus30 2
Morroni, Fabiana, Kitazawa, Masashi, Drago, Denise, Cheng, David, Medeiros, Rodrigo and LaFerla, Frank M. (2011) Repeated physical training and environmental enrichment induce neurogenesis and synaptogenesis following neuronal injury in an inducible mouse model. Journal of Behavioral and Brain Science, 1 4: 199-209. doi:10.4236/jbbs.2011.14027     0
Dunn, Haley C., Ager, Rahasson R., Baglietto-Vargas, David, Cheng, David, Kitazawa, Masashi, Cribbs, David H. and Medeiros, Rodrigo (2015) Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model. Journal of Alzheimers Disease, 43 3: 893-903. doi:10.3233/JAD-141335     32 Cited 33 times in Scopus33 1
Baglietto-Vargas, David, Chen, Yuncai, Suh, Dongjin, Ager, Rahasson R. , Rodriguez-Ortiz, Carlos J. , Medeiros, Rodrigo, Myczek, Kristoffer, Green, Kim N. , Baram, Tallie Z. and LaFerla, Frank M. (2015) Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice. Journal of Neurochemistry, 134 5: 915-926. doi:10.1111/jnc.13195     32 Cited 32 times in Scopus32 10
Passos, Giselle F., Medeiros, Rodrigo, Cheng, David, Vasilevko, Vitaly, LaFerla, Frank M. and Cribbs, David H. (2013) The bradykinin B1 receptor regulates Aβ deposition and neuroinflammation in Tg-SwDI mice. American Journal of Pathology, 182 5: 1740-1749. doi:10.1016/j.ajpath.2013.01.021     15 Cited 16 times in Scopus16 1
Nikkel, Arthur L., Martino, Brenda, Markosyan, Stella, Brederson, Jill-Desiree, Medeiros, Rodrigo, Moeller, Achim and Bitner, Robert S. (2012) The novel calpain inhibitor A-705253 prevents stress-induced tau hyperphosphorylation in vitro and in vivo. Neuropharmacology, 63 4: 606-612. doi:10.1016/j.neuropharm.2012.05.011     20 Cited 22 times in Scopus22 3
Passos, Giselle F., Medeiros, Rodrigo, Marcon, Rodrigo, Nascimento, Andrey F. Z., Calixto, Joao B. and Pianowski, Luiz F. (2013) The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice. European Journal of Pharmacology, 698 1-3: 413-420. doi:10.1016/j.ejphar.2012.10.019     34 Cited 37 times in Scopus37 1
Medeiros, Rodrigo, Baglietto-Vargas, David and LaFerla, Frank M. (2011) The role of tau in Alzheimer's disease and related disorders. CNS Neuroscience and Therapeutics, 17 5: 514-524. doi:10.1111/j.1755-5949.2010.00177.x     47 Cited 63 times in Scopus63 0
Bicca, M. A., Figueiredo, C. P., Piermartiri, T. C., Meotti, F. C., Bouzon, Z. L., Tasca, C. I., Medeiros, R. and Calixto, J. B. (2011) The selective and competitive N-methyl-D-aspartate receptor antagonist, (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid, prevents synaptic toxicity induced by β-amyloid in mice. Neuroscience, 192 631-641. doi:10.1016/j.neuroscience.2011.06.038     13 Cited 13 times in Scopus13 3
Kitazawa, Masashi, Medeiros, Rodrigo and LaFerla, Frank M. (2012) Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions. Current Pharmaceutical Design, 18 8: 1131-1147. doi:10.2174/138161212799315786     49 Cited 52 times in Scopus52 0