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Chua, Ming Jang, Do, Darren, Bachu, Prabhakar, Reid, Robert, Fairlie, David, Skinner-Adams, Tina and Andrews, Kathy (2017). Activity of the histone deacetylase (HDAC) inhibitor AR-42 in a murine malaria model. In: 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), Baltimore, MD United States, (493-493). 5-09 November 2017.     0
Trenholme, Katharine R., Brown, Christopher L., Skinner-Adams, Tina S., Stack, Colin, Lowther, Jonathan, To, Joyce, Robinson, Mark W., Donnelly, Sheila M., Dalton, John P. and Gardiner, Donald L. (2010) Aminopeptidases of malaria parasites: new targets for chemotherapy. Infectious Disorders - Drug Targets, 10 3: 217-225. doi:10.2174/187152610791163363     Cited 20 times in Scopus20 0
Hawthorne, Paula L., Trenholme, Katharine R., Skinner-Adams, Tina S., Spielmann, Tobias, Fischer, Katja, Dixon, Matthew W. A., Ortega, Maria R., Anderson, Karen L., Kemp, David J. and Gardiner, Donald L. (2004) A novel Plasmodium falciparum ring stage protein, REX, is located in Maurer's clefts. Molecular and Biochemical Parasitology, 136 2: 181-189. doi:10.1016/j.molbiopara.2004.03.013     73 Cited 71 times in Scopus71 0
Thivierge, Karine, Mathew, Rency T., Nsangou, Desire M. M., Da Silva, Fabio, Cotton, Sophie, Skinner-Adams, Tina S., Trenholme, Katharine R., Brown, Christopher L., Stack, Colin M., Gardiner, Donald L. and Dalton, John P. (2012) Anti-malaria drug development targeting the M1 alanyl and M17 leucyl aminopeptidases. Arkivoc, 2012 4: 330-346. doi:10.3998/ark.5550190.0013.424     2 Cited 2 times in Scopus2 0
Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012) Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 7: 3849-3856. doi:10.1128/AAC.00030-12     40 Cited 45 times in Scopus45 1
Peatey, Christopher L., Andrews, Katherine T., Eickel, Nina, MacDonald, Timothy, Butterworth, Alice S., Trenholme, Katharine R., Gardiner, Donald L., McCarthy, James S. and Skinner-Adams, Tina S. (2010) Antimalarial asexual stage-specific and gametocytocidal activities of HIV protease inhibitors. Antimicrobial Agents and Chemotherapy, 54 3: 1334-1337. doi:10.1128/AAC.01512-09     22 Cited 24 times in Scopus24 0
White, Andrew M., Pierens, Gregory K., Skinner-Adams, Tina, Andrews, Katherine T., Bernhardt, Paul V., Krenske, Elizabeth H., Mollo, Ernesto and Garson, Mary J. (2015) Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata. Journal of Natural Products, 78 6: 1422-1427. doi:10.1021/acs.jnatprod.5b00354     8 Cited 8 times in Scopus8 0
Skinner-Adams, Tina S., McCarthy, James S., Gardiner, Donald L., Hilton, Petrina M. and Andrews, Katherine T. (2004) Antiretrovirals as antimalarial agents. Journal of Infectious Diseases, 190 11: 1998-2000. doi:10.1086/425584     98 Cited 102 times in Scopus102 1
da Silva, Fabio L., Dixon, Matthew W. A., Stack, Colin M., Teuscher, Franka, Taran, Elena, Jones, Malcolm K., Lovas, Erica, Tilley, Leann, Brown, Christopher L., Trenholme, Katharine R., Dalton, John P., Gardiner, Donald L. and Skinner-Adams, Tina S. (2016) A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability. Experimental Parasitology, 169 13-21. doi:10.1016/j.exppara.2016.06.013     5 Cited 5 times in Scopus5 1
Savarino, Andrea, Cauda, Roberto, Cassone, Antonio, Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, J. James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors [3] (multiple letters). Journal of Infectious Diseases, 191 8: 1381-1383. doi:10.1086/428781     Cited 15 times in Scopus15
Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 8: 1382-1383. doi:10.1086/428782     3 Cited 15 times in Scopus15
White, Andrew M., Dao, Kathy, Vrubliauskas, Darius, Könst, Zef A., Pierens, Gregory K., Mándi, Attila, Andrews, Katherine T., Skinner-Adams, Tina S., Clarke, Mary E., Narbutas, Patrick T., Sim, Desmond C.-M., Cheney, Karen L., Kurtán, Tibor, Garson, Mary J. and Vanderwal, Christopher D. (2017) Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1. Journal of Organic Chemistry, 82 24: 13313-13323. doi:10.1021/acs.joc.7b02421     2 Cited 1 times in Scopus1 4
Stack, Colin M., Lowther, Jonathan, Cunningham, Eithne, Donnelly, Sheila, Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Teuscher, Franka, Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Lua, Linda, Bell, Angus and Dalton, John P. (2007) Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. Journal of Biological Chemistry, 282 3: 2069-2080. doi:10.1074/jbc.M609251200     78 Cited 77 times in Scopus77 0
Gardiner, Donald L., Spielmann, Tobias, Dixon, Matthew W. A., Hawthorne, Paula L., Ortega, Maria R., Anderson, Karen L., Skinner-Adams, Tina S., Kemp, David J. and Trenholme, Katharine R. (2004) CLAG 9 is located in the rhoptries of Plasmodium falciparum. Parasitology Research, 93 1: 64-67. doi:10.1007/s00436-004-1098-4     3 Cited 19 times in Scopus19 0
Skinner-Adams, Tina S., Lawrie, Paula M., Hawthorne, Paula L., Gardiner, Donald L. and Trenholme, Katharine R. (2003) Comparison of Plasmodium falciparum transfection methods. Malaria Journal, 2 1: 19.1-19.4. doi:10.1186/1475-2875-2-19     6 Cited 6 times in Scopus6 0
Skinner-Adams, Tina S, Lawrie, Paula M, Hawthorne, Paula L, Gardiner, Donald L and Trenholme, Katharine R (2003) Comparison of Plasmodium falciparum transfection methods. Malaria Journal, 2 1-4. doi:10.1186/1475-2875-2-1     Cited 6 times in Scopus6 0
Peatey, Christopher L., Skinner-Adams, Tina S., Dixon, Matthew W. A., McCarthy, James S., Gardiner, Donald L. and Trenholme, Katharine R. (2009) Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes. The Journal of Infectious Diseases, 200 10: 1518-1521. doi:10.1086/644645     51 Cited 58 times in Scopus58 3
Chua, Ming Jang, Arnold, Megan S. J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Spath, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S. and Andrews, Katherine T. (2017) Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth. International Journal for Parasitology: Drugs and Drug Resistance, 7 1: 42-50. doi:10.1016/j.ijpddr.2016.12.005     10 Cited 11 times in Scopus11 2
Poreba, Marcin, McGowan, Sheena, Skinner-Adams, Tina S., Trenholme, Katharine R., Gardiner, Donald L., Whisstock, James C., To, Joyce, Salvesen, Guy S., Dalton, John P. and Drag, Marcin (2012) Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. Plos One, 7 2: e31938-1-e31938-8. doi:10.1371/journal.pone.0031938     29 Cited 37 times in Scopus37 0
Skinner-Adams, Tina S., Hawthorne, Paula L., Trenholme, Katharine R. and Gardiner, Donald L. (2003) GATEWAY™ vectors for Plasmodium falciparum transfection. Trends in Parasitology, 19 1: 17-18. doi:10.1016/S1471-4922(02)00005-3     12 Cited 10 times in Scopus10 0
Porter, Kimberly A., Cole, Stephen R., Eron, Joseph J., Jr., Zheng, Yu, Hughes, Michael D., Lockman, Shahin, Poole, Charles, Skinner-Adams, Tina S., Hosseinipour, Mina, Shaffer, Doug, D'Amico, Ronald, Sawe, Frederick K., Siika, Abraham, Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, McCarthy, James S. and Meshnicka, Steven R. (2012) HIV-1 protease inhibitors and clinical malaria: A secondary analysis of the AIDS Clinical Trials Group A5208 study. Antimicrobial Agents and Chemotherapy, 56 2: 995-1000. doi:10.1128/AAC.05322-11     13 Cited 13 times in Scopus13 1
Skinner-Adams, Tina S., Lowther, Jonathan, Teuscher, Franka, Stack, Colin M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, Trenholme, Katharine R., Dalton, John P. and Gardiner, Donald L. (2007) Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. Journal of Medicinal Chemistry, 50 24: 6024-6031. doi:10.1021/jm070733v     53 Cited 53 times in Scopus53 0
Gardiner, Donald L., Dixon, Matthew W. A., Spielmann, Tobias, Skinner-Adams, Tina S., Hawthorne, Paula L., Ortega, Maria R., Kemp, David J. and Trenholme, Katharine R. (2005) Implication of a Plasmodium falciparum gene in the switch between asexual reproduction and gametocytogenesis. Molecular and Biochemical Parasitology, 140 2: 153-160. doi:10.1016/j.molbiopara.2004.12.010     25 Cited 25 times in Scopus25 0
Keough, Dianne T., Hockova, Dana, Holy, Antonin, Naesens, Lieve M. J., Skinner-Adams, Tina S., de Jersey, John and Guddat, Luke W. (2009) Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry, 52 14: 4391-4399. doi:10.1021/jm900267n     70 Cited 69 times in Scopus69 9
Keough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin., Brereton, Ian M., Guddat, Luke W. and de Jersey, John (2006) Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry, 49 25: 7479-7486. doi:10.1021/jm061012j     40 Cited 39 times in Scopus39 0
Trenholme, Katharine, Marek, Linda, Duffy, Sandra, Pradel, Gabriele, Fisher, Gillian, Hansen, Finn K., Skinner-Adams, Tina S., Butterworth, Alice, Ngwa, Che Julius, Moecking, Jonas, Goodman, Christopher D., McFadden, Geoffrey I., Sumanadasa, Subathdrage D. M., Fairlie, David P., Avery, Vicky M., Kurz, Thomas and Andrews, Katherine T. (2014) Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules. Antimicrobial Agents and Chemotherapy, 58 7: 3666-3678. doi:10.1128/AAC.02721-13     26 Cited 28 times in Scopus28 3
Gardiner, Donald L., Skinner-Adams, Tina S., Spielmann, Tobias and Trenholme, Katharine R. (2003) Malaria transfection and transfection vectors. Trends In Parasitology, 19 9: 381-383. doi:10.1016/S1471-4922(03)00187-9     22 Cited 24 times in Scopus24 0
Raju, Ritesh, Khalil, Zeinab G., Piggott, Andrew M., Blumenthal, Antje, Gardiner, Donald L., Skinner-Adams, Tina S. and Capon, Robert J. (2014) Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide-polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244). Organic Letters, 16 6: 1716-1719. doi:10.1021/ol5003913     10 Cited 11 times in Scopus11 1
Gardiner, Donald L., Trenholme, Katharine R., Skinner-Adams, Tina S., Stack, Colin M. and Dalton, John P. (2006) Overexpression of Leucyl Aminopeptidase in Plasmodium falciparum Parasites. Target for the antimalarial activity of bestatin. Journal of Biological Chemistry, 281 3: 1741-1745. doi:10.1074/jbc.M508955200     51 Cited 52 times in Scopus52 1
Butterworth, Alice S., Skinner-Adams, Tina S., Gardiner, Don L. and Trenholme, Katharine R. (2013) Plasmodium falciparum gametocytes: With a view to a kill. Parasitology, 140 14: 1718-1734. doi:10.1017/S0031182013001236     15 Cited 13 times in Scopus13 2
Andrews, Kathy T., Tran, Thanh N., Lucke, Andrew, Kahnberg, Pia, Lee, G. T., Skinner-Adams, Tina, Gardiner, Donald L. and Fairlie, David P. (2007). Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets. In: Abstract Book: American Society of Tropical Medicine and Hygiene : 56th Annual Meeting. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia, PA United States, (48-48). 04-08 November 2007.     0
Gardiner, Donald L., Skinner-Adams, Tina S., Brown, Christopher L., Andrews, Katherine T., Stack, Colin M., McCarthy, James S., Dalton, John P. and Trenholme, Katharine R. (2009) Plasmodium falciparum: New molecular targets with potential for antimalarial drug development. Expert Review of Anti-Infective Therapy, 7 9: 1087-1098. doi:10.1586/ERI.09.93     19 Cited 19 times in Scopus19 0
Vu, Hoan, Roullier, Catherine, Campitelli, Marc, Trenholme, Katharine R., Gardiner, Donald L., Andrews, Katherine T., Skinner-Adams, Tina, Crowther, Gregory J., Van Voorhis, Wesley C. and Quinn, Ronald J. (2013) Plasmodium gametocyte inhibition identified from a natural-product-based fragment library. ACS Chemical Biology, 8 12: 2654-2659. doi:10.1021/cb400582b     11 Cited 15 times in Scopus15 8
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006) Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 2: 639-648. doi:10.1128/AAC.50.2.639-648.2006     101 Cited 108 times in Scopus108 4
Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D. M., Ng, Susanna S., Fairlie, David P., Skinner-Adams, Tina and Andrews, Katherine T. (2016) Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites (vol 5, pg 117, 2015). International Journal for Parasitology-Drugs and Drug Resistance, 6 3: 287-287. doi:10.1016/j.ijpddr.2016.05.001     0 0
Mudianta, I. Wayan, Skinner-Adams, Tina, Andrews, Katherine T., Davis, Rohan A., Hadi, Tri A., Hayes, Patricia Y. and Garson, Mary J. (2012) Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata. Journal of Natural Products, 75 12: 2132-2143. doi:10.1021/np300560b     12 Cited 15 times in Scopus15 3
Martin, Rowena E., Butterworth, Alice S., Gardiner, Donald L., Kirk, Kiaran, McCarthy, James S. and Skinner-Adams, Tina S. (2012) Saquinavir Inhibits the malaria parasite's chloroquine resistance transporter. Antimicrobial Agents and Chemotherapy, 56 5: 2283-2289. doi:10.1128/AAC.00166-12     18 Cited 18 times in Scopus18 0
McGowan, Sheena, Porter, Corrine J., Lowther, Jonathan, Stack, Colin M., Golding, Sarah J., Skinner-Adams, Tina S., Trenholme, Katharine R., Teuscher, Franka, Donnelly, Sheila M., Grembecka, Jolanta, Mucha, Artur, Kafarski, Pawel, DeGori, Ross, Buckle, Ashley M., Gardiner, Donald L., Whisstock, James C. and Dalton, John P. (2009) Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proceedings of the National Academy of Sciences of USA, 106 8: 2537-2542. doi:10.1073/pnas.0807398106     84 Cited 88 times in Scopus88 10
Skinner-Adams, Tina S., Peatey, Christopher L., Anderson, Karen, Trenholme, Katharine R., Krige, David, Brown, Christopher L., Stack, Colin, Nsangou, Desire M. M., Mathews, Rency T., Thivierge, Karine, Dalton, John P. and Gardinerd, Donald L. (2012) The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria. Antimicrobial Agents and Chemotherapy, 56 6: 3244-3249. doi:10.1128/AAC.06245-11     18 Cited 18 times in Scopus18 1
Skinner-Adams,Tina S., Butterworth, Alice S., Porter, Kimberly A., D'Amico, Ronald, Sawe, Fred, Shaffer, Doug, Siika, Abraham, Hosseinipour, Mina C., Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, Lockman, Shahin, Eron, Joseph J., Meshnick, Steven R. and McCarthy, James S. (2012) The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment. PLoS One, 7 4 Article No. e34399: e34399-1-e34399-4. doi:10.1371/journal.pone.0034399     12 Cited 11 times in Scopus11 1