Failure of Normal Glycaemic Regulation in a Patient With Severe Hypothermia

Pfeifer, Robert Nicholas Chantler (2005) Failure of Normal Glycaemic Regulation in a Patient With Severe Hypothermia.

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Title Failure of Normal Glycaemic Regulation in a Patient With Severe Hypothermia
Abstract/Summary This report describes the case of an 88-year-old non-diabetic female who presented to the emergency department severely hypothermic following a presumed hypoglycaemic collapse due to self-neglect. Subsequent rewarming and resuscitation demonstrated a number of the significant consequences of severe hypothermia, including apparent secondary impairment of glycaemic autoregulation. The phenomenon of reversible inhibition of insulin secretion due to severe hypothermia has previously been documented in the field of cardiac surgery. The hyperglycaemia was not treated with any antihyperglycaemic agent, and her recovery was uneventful. Subsequent blood sugar level monitoring was normal. If administering insulin to the hypothermic patient, intensive monitoring of blood glucose is essential due to the increase in endogenous insulin secretion on rewarming.
Keyword hypothermia
hyperglycaemia
hypoglycaemia
Date 2005-05-01
Subjects 320603 Systems Physiology
321004 Endocrinology
Author Pfeifer, Robert Nicholas Chantler
Open Access Status Other
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Additional Notes Publication pending in Resuscitation (Elsevier). http://dx.doi.org/10.1016/j.resuscitation.2005.05.016 Alternative Location

Document type: Preprint
Collection: School of Medicine Publications
 
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Created: Fri, 15 Jul 2005, 10:00:00 EST by Robert Nicholas Chantler Pfeifer on behalf of School of Medicine