Airway sizes and proportions in children quantified by a video-bronchoscopic technique

Masters, Ian B., Ware, Robert S., Zimmerman, Paul V., Lovell, Brian, Wootton, Richard, Francis, Paul V. and Chang, Anne B. (2006) Airway sizes and proportions in children quantified by a video-bronchoscopic technique. BMC Pulmonary Medicine, 6 5: 1-8. doi:10.1186/1471-2466-6-5

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Author Masters, Ian B.
Ware, Robert S.
Zimmerman, Paul V.
Lovell, Brian
Wootton, Richard
Francis, Paul V.
Chang, Anne B.
Title Airway sizes and proportions in children quantified by a video-bronchoscopic technique
Journal name BMC Pulmonary Medicine   Check publisher's open access policy
ISSN 1471-2466
Publication date 2006-01-01
Sub-type Article (original research)
DOI 10.1186/1471-2466-6-5
Volume 6
Issue 5
Start page 1
End page 8
Total pages 8
Editor D. Saltman
Place of publication U.K.
Publisher BioMed Central
Collection year 2006
Language eng
Subject 321019 Paediatrics
280208 Computer Vision
321027 Respiratory Diseases
730110 Respiratory system and diseases (incl. asthma)
C1
Abstract Background: A quantitative understanding of airway sizes and proportions and a reference point for comparisons are important to a bronchoscopist. The aims of this study were to measure large airway areas, and define proportions and predictors of airway size in children. Methods: A validated videobronchoscope technique was used to measure in-vivo airway cross-sectional areas (cricoid, right (RMS) and left (LMS) main stem and major lobar bronchi) of 125 children. Airway proportions were calculated as ratios of airways to cricoid areas and to endotracheal tube (ETT) areas. Mann Whitney U, T-tests, and one-way ANOVA were used for comparisons and standard univariate and backwards, stepwise multivariate regression analyses were used to define airway size predictors. Results: Airways size increased progressively with increasing age but proportions remained constant. The LMS was 21% smaller than the RMS. Gender differences in airways' size were not significant in any age group or airway site. Cricoid area related best to body length (BL): cricoid area (mm2) = 26.782 + 0.254*BL (cm) while the RMS and LMS area related best to weight: RMS area (mm2) = 23.938 + 0.394*Wt (kg) and LMS area (mm2) = 20.055 + 0.263*Wt (kg) respectively. Airways to cricoid ratios were larger than airway to ETT ratios (p=0.0001). Conclusions: The cricoid and large airways progressively increase in size but maintain constant proportional relationships to the cricoid across childhood. The cricoid area correlates with body length while the RMS and LMS are best predicted by weight. These data provide for quantitative comparisons of airway lesions.
Keyword Iris-research
Airways
Bronchoscope
Predictors
Size
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