Insulin sensitivity measures in cats exhibit high inter-day variability

Coradini, M., Rand, J. S., Morton, J. M., Litster, L. and Rawlings, M. (2006). Insulin sensitivity measures in cats exhibit high inter-day variability. In: K. W. Hinchcliff, Research Abstract Program of the 24th Annual ACVIM Forum: Abstracts published in the Journal of Veterinary Internal Medicine. Array, Louisville, KY, (770-770). 31 May - 3 June 2006.


Author Coradini, M.
Rand, J. S.
Morton, J. M.
Litster, L.
Rawlings, M.
Title of paper Insulin sensitivity measures in cats exhibit high inter-day variability
Conference name Array
Conference location Louisville, KY
Conference dates 31 May - 3 June 2006
Proceedings title Research Abstract Program of the 24th Annual ACVIM Forum: Abstracts published in the Journal of Veterinary Internal Medicine   Check publisher's open access policy
Journal name Journal of Veterinary Internal Medicine   Check publisher's open access policy
Place of Publication Hoboken, N.J.
Publisher Wiley
Publication Year 2006
Sub-type Published abstract
Open Access Status Link (no DOI)
ISSN 0891-6640
Editor K. W. Hinchcliff
Volume 20
Issue 3
Start page 770
End page 770
Total pages 1
Language eng
Abstract/Summary In cats with underlying low insulin sensitivity, obesity is a major risk factor for type 2 diabetes. Strategies to prevent the onset of type 2 diabetes could be implemented if these cats could be identified. Currently, two labour-intensive and complex methods have been used to measure insulin sensitivity in research studies: the hyperinsulinemic euglycemic clamp (Clamp) and the minimal model analysis (MINMOD) of a frequentlysampled intravenous glucose tolerance test. However, simpler measures are required in practice. Validation of simple measures requires a wellestablished method with minimal inter-day variability. The aims of this study were to determine the inter-day variability of the current methods of measuring insulin sensitivity in cats, and to assess the relationship between these tests and simpler measures of insulin sensitivity.
Subjects CX
300501 Veterinary Medicine
780105 Biological sciences
070704 Veterinary Epidemiology
Keyword insulin
sensitivity
cats
high
variability
Q-Index Code CX

 
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Created: Wed, 15 Aug 2007, 10:46:06 EST