Pyrrolizidine alkaloids in Senecio madagascariensis from Australia and Hawaii and assessment of possible livestock poisoning

Gardner, Dale R., Thorne, Mark S., Molyneux, Russell J., Pfister, James A. and Seawright, Alan A. (2006) Pyrrolizidine alkaloids in Senecio madagascariensis from Australia and Hawaii and assessment of possible livestock poisoning. Biochemical Systematics and Ecology, 34 10: 736-744. doi:10.1016/j.bse.2006.05.010


Author Gardner, Dale R.
Thorne, Mark S.
Molyneux, Russell J.
Pfister, James A.
Seawright, Alan A.
Title Pyrrolizidine alkaloids in Senecio madagascariensis from Australia and Hawaii and assessment of possible livestock poisoning
Formatted title
Pyrrolizidine alkaloids in Senecio madagascariensis from Australia and Hawaii and assessment of possible livestock poisoning
Journal name Biochemical Systematics and Ecology   Check publisher's open access policy
ISSN 0305-1978
1873-2925
Publication date 2006-10
Sub-type Article (original research)
DOI 10.1016/j.bse.2006.05.010
Volume 34
Issue 10
Start page 736
End page 744
Total pages 9
Place of publication Oxford, United Kingdom
Publisher Pergamon
Collection year 2006
Language eng
Subject 321299 Public Health and Health Services not elsewhere classified
730299 Public health not elsewhere classified
Abstract The alkaloid content of Senecio madagascariensis collected from Australia and Hawaii was examined. Alkaloids were identified from the above ground whole plant (stems, leaves and flowers) by GUMS analysis and included: senecivernine, senecionine, integerrimine, senkirkine, mucronatinine, retrosine, usaramine, otosenine, acetylsenkirkine, desacetyldoronine, florosenine and doronine. Plant material collected from the Hawaiian Islands was found to be identical in pyrrolizidine alkaloid content to that from a single composite collection made from northern New South Wales, Australia. Overall, no appreciable differences in alkaloid content were found between locations, whereas variation among individual plants was evident. The average total pyrrolizidine alkaloid content varied from a low of 217 mu g/g to a high of 1990 mu g/g (dry weight basis) among the locations. Based on comparable alkaloid content and documented pyrrolizidine alkaloidosis cases from Australia, S. madagascariensis may pose a significant risk to livestock grazing heavily infested ranges on the Hawaiian Islands. (c) 2006 Elsevier Ltd. All rights reserved.
Keyword Senecio Madagascariensis
Pyrrolizidine Alkaloids
Livestock Poisoning
Hepatoxicity
Hawaii
Australia
References Senecio madagascariensis; Pyrrolizidine alkaloids; Livestock poisoning; Hepatotoxicity; Hawaii; Australia
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2007 Higher Education Research Data Collection
National Research Centre for Environmental Toxicology Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 28 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 32 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 15 Aug 2007, 10:36:34 EST