Influence of arterial compliance on presence and extent of ischaemia during stress echocardiography

Haluska, B. A., Matthys, K., Fathi, R., Rozis, E., Carlier, S. G. and Marwick, T. H. (2006) Influence of arterial compliance on presence and extent of ischaemia during stress echocardiography. Heart, 92 1: 40-43. doi:10.1136/hrt.2004.052209

Author Haluska, B. A.
Matthys, K.
Fathi, R.
Rozis, E.
Carlier, S. G.
Marwick, T. H.
Title Influence of arterial compliance on presence and extent of ischaemia during stress echocardiography
Journal name Heart   Check publisher's open access policy
ISSN 1355-6037
Publication date 2006-01
Sub-type Article (original research)
DOI 10.1136/hrt.2004.052209
Volume 92
Issue 1
Start page 40
End page 43
Total pages 4
Editor R. J. Hall
Place of publication London, U.K.
Publisher BMJ Publishing Group
Collection year 2006
Language eng
Subject C1
321003 Cardiology (incl. Cardiovascular Diseases)
730106 Cardiovascular system and diseases
1102 Cardiovascular Medicine and Haematology
Abstract Objective: To seek an association between total arterial compliance (TAC) and the extent of ischaemia at stress echocardiography. Design: Cohort study. Setting: Regional cardiac centre. Methods: 255 consecutive patients (147 men; mean (SD) age 58 (8)) presenting for stress echocardiography for clinical indications were studied. Wall motion score index (WMSI) was calculated and ischaemia was defined by an inducible or worsening wall motion abnormality. Peak WMSI was used to reflect the extent of dysfunction (ischaemia or scar), and Delta WMSI was indicative of extent of ischaemia. TAC was assessed at rest by simultaneous radial applanation tonometry and pulsed wave Doppler in all patients. Results: Ischaemia was identified by stress echocardiography in 65 patients (25%). TAC was similar in the groups with negative and positive echocardiograms (1.08 (0.41) v 1.17 (0.51) ml/ mm Hg, not significant). However, the extent of dysfunction was associated with TAC independently of age, blood pressure, risk factors, and use of a beta blocker. Moreover, the extent of ischaemia was determined by TAC, risk factors, and use of a b blocker. Conclusion: While traditional cardiovascular risk factors are strong predictors of ischaemia on stress echocardiography, TAC is an independent predictor of the extent of ischaemia.
Keyword Cardiac & cardiovascular systems
Aortic compliance
Pulse pressure
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
2007 Higher Education Research Data Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 15 Aug 2007, 09:56:28 EST