World Association for the Advancement of Veterinary Parasitology (WAAVP) guidelines for evaluating the efficacy of acaricides against ticks (Ixodidae) on ruminants

Holdsworth, P. A., Kemp, D., Green, P., Peter, R. J., De Bruin, C., Jonsson, N. N., Letonja,T., Rehbein,S. and Vercruysse, J. (2006) World Association for the Advancement of Veterinary Parasitology (WAAVP) guidelines for evaluating the efficacy of acaricides against ticks (Ixodidae) on ruminants. Veterinary Parasitology, 136 1: 29-43. doi:10.1016/j.vetpar.2005.11.011


Author Holdsworth, P. A.
Kemp, D.
Green, P.
Peter, R. J.
De Bruin, C.
Jonsson, N. N.
Letonja,T.
Rehbein,S.
Vercruysse, J.
Title World Association for the Advancement of Veterinary Parasitology (WAAVP) guidelines for evaluating the efficacy of acaricides against ticks (Ixodidae) on ruminants
Journal name Veterinary Parasitology   Check publisher's open access policy
ISSN 0304-4017
Publication date 2006
Sub-type Article (original research)
DOI 10.1016/j.vetpar.2005.11.011
Volume 136
Issue 1
Start page 29
End page 43
Total pages 15
Editor L. S. Mansfield
Place of publication Amsterdam
Publisher Elsevier Science
Collection year 2006
Language eng
Subject 300508 Parasitology
630107 Minor livestock (e.g. horses, goats, deer)
Abstract These guidelines have been prepared to assist in the planning, conduct and interpretation of studies for the assessment of the efficacy of acaricides (excluding vaccines and other bio-control agents) against single and multi-host ticks (Ixodidae) on ruminants. Information is provided on the selection of animals, dose determination, dose confirmation and field studies, record keeping and result interpretation. The use of pen facilities is advocated for dose determination and confirmation studies for defining therapeutic and persistent efficacy. A minimum of two studies per tick species for which claims are sought is recommended for each dose determination and dose confirmation investigation. If dose confirmation studies demonstrate greater than 95% efficacy the sponsor may proceed to field studies, where a minimum of two studies per geographical location is preferred to confirm the therapeutic and persistent efficacy under field conditions. If dose confirmation studies demonstrate less than 95% efficacy then longer-term field studies can be conducted over two tick seasons with a minimum of two studies per geographical location. These studies can incorporate other control methods such as tick vaccines, to demonstrate stable long-term tick management. Specific advice is also given on conducting studies with paralysis ticks. These guidelines are also intended to assist investigators on how to conduct specific experiments, to provide specific information for registration authorities involved in the decision-making process, to assist in the approval and registration of new acaricides, and to facilitate the worldwide adoption of standard procedures. (c) 2005 Elsevier B.V. All rights reserved.
Keyword Acaricides
Ruminants
Ticks
Therapeutic Efficacy
Persistent Efficacy
Strategic Management Program
Guidelines
Parasitology
Veterinary Sciences
Anthelmintics
Microplus
Chickens
Turkeys
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

 
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Created: Wed, 15 Aug 2007, 09:38:31 EST