Transgenic gene silencing strategies for virus control

DietzgenRG and Mitter, N. (2006) Transgenic gene silencing strategies for virus control. Australasian Plant Pathology, 35 6: 605-618. doi:10.1071/AP06064

Author DietzgenRG
Mitter, N.
Title Transgenic gene silencing strategies for virus control
Journal name Australasian Plant Pathology   Check publisher's open access policy
ISSN 0815-3191
Publication date 2006
Sub-type Article (original research)
DOI 10.1071/AP06064
Volume 35
Issue 6
Start page 605
End page 618
Total pages 14
Place of publication Collingwood
Publisher CSIRO Publishing
Collection year 2006
Language eng
Subject CX
Abstract Co-suppression of transgenes and their homologous viral sequences by RNA silencing is a powerful strategy for achieving high-level virus resistance in plants. This review provides a brief overview of RNA silencing mechanisms in plants and discusses important transgene construct design features underpinning successful RNA silencing-mediated transgenic virus control. Application of those strategies to protect horticultural and field crops from virus infection and results of field tests are also provided. The effectiveness and stability of RNA-mediated transgenic resistance are assessed taking into account effects of viral, plant and environmental factors.
Keyword double-stranded RNA
RNA interference
silencing suppressors
small interfering RNA
transgenic crops
Q-Index Code CX

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Integrative Legume Research Publications
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Citation counts: TR Web of Science Citation Count  Cited 7 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 15 Aug 2007, 09:26:00 EST