Pre-term delivery and periodontal disease: a case-control study from Croatia

Bosnjak, A., Relja, T., Vucicevic-Boras, V., Plasaj, H. and Plancak, D. (2006) Pre-term delivery and periodontal disease: a case-control study from Croatia. Journal of Clinical Periodontology, 33 10: 710-716. doi:10.1111/j.1600-051X.2006.00977.x

Author Bosnjak, A.
Relja, T.
Vucicevic-Boras, V.
Plasaj, H.
Plancak, D.
Title Pre-term delivery and periodontal disease: a case-control study from Croatia
Journal name Journal of Clinical Periodontology   Check publisher's open access policy
ISSN 0303-6979
Publication date 2006
Sub-type Article (original research)
DOI 10.1111/j.1600-051X.2006.00977.x
Volume 33
Issue 10
Start page 710
End page 716
Total pages 7
Editor J. Lindhe
M. Tonetti
Place of publication Denmakr
Publisher Blackwell Munksgaard
Collection year 2006
Language eng
Subject C1
320899 Dentistry not elsewhere classified
730112 Oro-dental and disorders
1105 Dentistry
Abstract Aim: The aim of this report was to assess the strength and influence of periodontitis as a possible risk factor for pre-term birth (PTB) in a cohort of 81 primiparous Croatian mothers aged 18-39 years. Methods: PTB cases (n=17; mean age 25 +/- 2.9 years; age range 20-33 years) were defined as spontaneous delivery after less than 37 completed weeks of gestation that were followed by spontaneous labour or spontaneous rupture of membranes. Controls (full-time births) were normal births at or after 37 weeks of gestation (n=64; mean age 25 +/- 2.9 years; age range 19-39 years). Information on known risk factors and obstetric factors included the current pregnancy history, maternal age at delivery, pre-natal care, nutritional status, tobacco use, alcohol use, genitourinary infections, vaginosis, gestational age, and birth weight. Full-mouth periodontal examination was performed on all mothers within 2 days of delivery. Results: PTB cases had significantly worse periodontal status than controls (p=0.008). Multivariate logistic regression model, after controlling for other risk factors, demonstrated that periodontal disease is a significant independent risk factor for PTB, with an adjusted odds ratio of 8.13 for the PTB group (95% confidence interval 2.73-45.9). Conclusion: Periodontal disease represents a strong, independent, and clinically significant risk factor for PTB in the studied cohort. There are strong indicators that periodontal therapy should form a part of preventive prenatal care in Croatia.
Keyword Demographics
Pre-term Birth
Risk Factors
Dentistry, Oral Surgery & Medicine
Bacterial Vaginosis
Premature Rupture
Controlled Trial
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2007 Higher Education Research Data Collection
School of Dentistry Publications
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Citation counts: TR Web of Science Citation Count  Cited 25 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 32 times in Scopus Article | Citations
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Created: Wed, 15 Aug 2007, 09:04:18 EST