Long-term persistence of multi-drug-resistant Salmonella enterica serovar Newport in two dairy herds

Cobbold, Rowland N., Rice, Daniel H., Davis, Margaret A., Besser, Thomas E and Hancock, Dale D. (2006) Long-term persistence of multi-drug-resistant Salmonella enterica serovar Newport in two dairy herds. Journal of The American Veterinary Medical Association, 228 4: 585-591.

Document type: Journal Article
Sub-type: Article
Collections: Excellence in Research Australia (ERA) - Collection
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Author Cobbold, Rowland N.
Rice, Daniel H.
Davis, Margaret A.
Besser, Thomas E
Hancock, Dale D.
Title Long-term persistence of multi-drug-resistant Salmonella enterica serovar Newport in two dairy herds
Journal name Journal of The American Veterinary Medical Association  (ERA 2012 Listed)    (ERA 2010 Rank B)
Publication date 2006-02
Sub-type Article
Volume number 228
Issue number 4
ISSN 0003-1488
Start page 585
End page 591
Total pages 7
Editor Amy Voigt
Place of publication Schaumburg
Publisher American Veterinary Medical Association
Collection year 2006
Language eng
Subject 321206 Preventive Medicine
320403 Medical Infection Agents (incl. Prions)
630104 Dairy cattle
730101 Infectious diseases
070205 Animal Protection (Pests and Pathogens)
C1
Abstract Objective - To evaluate the association between maintaining joint hospital and maternity pens;and persistence of multi-drug-resistant (MDR) Salmonella enterica serovar Newport on 2 dairy farms. Design - Observational study. Sample Population - Feces and environmental samples from 2 dairy herds. Procedure - Herds were monitored for fecal shedding of S enterica Newport after outbreaks of clinical disease. Fecal and environmental samples were collected approximately monthly from pens housing sick cows and calving cows and from pens containing lactating cows. Cattle shedding the organism were tested serially on subsequent visits to determine carrier status. One farm was resampled after initiation of interventional procedures, including separation of hospital and maternity pens. Isolates were characterized via serotyping, determination of antimicrobial resistance phenotype, detection of the CMY-2 gene, and DNA fingerprinting. Results - The prevalence (32.4% and 33.3% on farms A and B, respectively) of isolating Salmonella from samples from joint hospital-maternity pens was significantly higher than the prevalence in samples from pens housing preparturient cows (0.8%, both farms) and postparturient cows on Farm B (8.8%). Multi-drug-resistant Salmonella Newport was isolated in high numbers from bedding material, feed refusals, lagoon slurry, and milk filters. One cow excreted the organism for 190 days. Interventional procedures yielded significant reductions in the prevalences of isolating the organism from fecal and environmental samples. Most isolates were of the C2 serogroup and were resistant to third-generation cephalosporins. Conclusions and Clinical Relevance - Management practices may be effective at reducing the persistence of MDR Salmonella spp in dairy herds, thus mitigating animal and public health risk.
Keyword Multi-drug-resistant
Salmonella
Dairy Herds
Veterinary Sciences
Clinical Salmonellosis
Typhimurium Dt104
Escherichia-coli
United-states
Risk-factors
Food Animals
Infection
Cattle
Expression
Outbreak
Q-Index Code C1
 
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Citation counts: Thomson Reuters Citation Count Cited 26 times in Thomson Reuters Researcher ID
Scopus Citation Count Cited 26 times in Scopus
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