Failure of normal glycaemic regulation in a patient with severe hypothermia

Pfeifer, Robert Nicholas Chantler (2006) Failure of normal glycaemic regulation in a patient with severe hypothermia. Resuscitation, 68 1: 139-142. doi:10.1016/j.resuscitation.2005.05.016

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Author Pfeifer, Robert Nicholas Chantler
Title Failure of normal glycaemic regulation in a patient with severe hypothermia
Journal name Resuscitation   Check publisher's open access policy
ISSN 0300-9572
Publication date 2006
Sub-type Article (original research)
DOI 10.1016/j.resuscitation.2005.05.016
Open Access Status File (Author Post-print)
Volume 68
Issue 1
Start page 139
End page 142
Total pages 4
Place of publication Clare
Publisher Elsevier Ireland Ltd
Collection year 2006
Language eng
Subject CX
321004 Endocrinology
Abstract This report describes the case of an 88-year-old non-diabetic female who presented to the emergency department following a presumed hypoijtycaemic collapse due to self-neglect. Subsequent rewarming and resuscitation demonstrated a number of the significant consequences of severe hypothermia, including apparent secondary impairment of glycaemic autoregulation. The phenomenon of reversible inhibition of insulin secretion due to severe hypothermia has been documented previously in the field of cardiac surgery. The hyperglycaemia was not treated with any antihyperglycaernic agent, and her recovery was uneventful. Subsequent blood sugar level monitoring was normal. If insulin is administered to the hypothermic patient, intensive monitoring of blood glucose is essential due to the increase in endogenous insulin secretion on rewarming. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
Keyword Hypothermia
Critical Care Medicine
Emergency Medicine
Open-heart Surgery
Cardiopulmonary Bypass
Q-Index Code CX

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Wed, 15 Aug 2007, 08:45:20 EST