Disrupted cortical proprioceptive representation evokes symptoms of peculiarity, foreignness and swelling, but not pain

Moseley, G. L., McCormick, K. E., Hudson, M. and Zalucki, N (2006) Disrupted cortical proprioceptive representation evokes symptoms of peculiarity, foreignness and swelling, but not pain. Rheumatology, 45 2: 196-200. doi:10.1093/rheumatology/kei119


Author Moseley, G. L.
McCormick, K. E.
Hudson, M.
Zalucki, N
Title Disrupted cortical proprioceptive representation evokes symptoms of peculiarity, foreignness and swelling, but not pain
Journal name Rheumatology   Check publisher's open access policy
ISSN 1462-0324
Publication date 2006
Sub-type Article (original research)
DOI 10.1093/rheumatology/kei119
Volume 45
Issue 2
Start page 196
End page 200
Total pages 5
Editor F. Hiepe
Place of publication Oxford
Publisher Oxford Univ Press
Collection year 2006
Language eng
Subject C1
321024 Rehabilitation and Therapy - Occupational and Physical
730303 Occupational, speech and physiotherapy
1103 Clinical Sciences
Abstract Objectives. It has been proposed that disruption of the internal proprioceptive representation, via incongruent sensory input, may underpin pathological pain states, but experimental evidence relies on conflicting visual input, which is not clinically relevant. We aimed to determine the symptomatic effect of incongruent proprioceptive input, imparted by vibration of the wrist tendons, which evokes the illusion of perpetual wrist flexion and disrupts cortical proprioceptive representation. Methods. Twenty-nine healthy and naive volunteers reported symptoms during five conditions: control, active and passive wrist flexion, extensor carpi radialis tendon vibration to evoke illusion of perpetual wrist flexion, and ulnar styloid (sham) vibration. No advice was given about possible illusions. Results. Twenty-one subjects reported the illusion of perpetual wrist flexion during tendon vibration. There was no effect of condition or of whether or not subjects reported an illusion on discomfort/pain (P > 0.28). Peculiarity, swelling and foreignness were greater during tendon vibration than during the other conditions, and greater during tendon vibration in those who reported an illusion of wrist flexion than in those who did not (P < 0.05 for all). Symptoms were reported by at least two subjects in each condition and four subjects reported systemic symptoms (e.g. nausea). Conclusions. In healthy volunteers, incongruent proprioceptive input does not cause discomfort or pain but does evoke feelings of peculiarity, swelling and foreignness in the limb.
Keyword body schema
pathological pain
sensory-motor incongruence
cortical organization
vibration
illusion
Syndrome Crps
Body-image
Reorganization
Abnormalities
Cortex
Hand
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2007 Higher Education Research Data Collection
School of Public Health Publications
 
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Created: Wed, 15 Aug 2007, 08:37:51 EST