Anesthesia of captive African wild dogs (Lycaon pictus) using a medetomidine-ketamine-atropine combination

Ward, David G., Blyde, David, Lemon, John and Johnston, Steve (2006) Anesthesia of captive African wild dogs (Lycaon pictus) using a medetomidine-ketamine-atropine combination. Journal of Zoo And Wildlife Medicine, 37 2: 160-164. doi:10.1638/05-037.1

Author Ward, David G.
Blyde, David
Lemon, John
Johnston, Steve
Title Anesthesia of captive African wild dogs (Lycaon pictus) using a medetomidine-ketamine-atropine combination
Journal name Journal of Zoo And Wildlife Medicine   Check publisher's open access policy
ISSN 1042-7260
Publication date 2006
Sub-type Article (original research)
DOI 10.1638/05-037.1
Volume 37
Issue 2
Start page 160
End page 164
Total pages 5
Editor Wilbur B. Amand
Place of publication Media
Publisher Amer Assoc Zoo Veterinarians
Collection year 2006
Language eng
Subject C1
300502 Anaesthesiology and Intensive Care
780105 Biological sciences
070701 Veterinary Anaesthesiology and Intensive Care
Abstract Seven captive male African wild dogs (Lycaon pictus) weighing 25-32 kg each, were anesthetized by i.m. injection via hand syringe with a combination of 1.5 mg/kg ketamine, 40 mu g/kg medetomidine, and 0.05 mg/kg atropine. Following endotracheal intubation, each animal was connected to a bain closed-circuit system that delivered 1.5% isoflurane and 2 L/min oxygen. Atipamezole (0.1 mg/kg i.v.; 0.1 mg/kg i.m.) was given at the end of each procedure (60 min following injection of medetomidine/ketamine/atropine). Time to sternal recumbency was 5-8 min. Times to standing after atipamezole administration were 8-20 min. This anesthetic regimen was repeated on three separate occasions (September 2000, February 2002, and October 2002) on all males to perform electroejaculation procedures. Each procedure was < 80 min from injection to standing. Dogs showed excellent muscle relaxation during the procedures. Arterial blood samples were collected at 10-min intervals for blood gases in one procedure (September 2000). Separate venous samples were taken from each dog during each procedure for hematology and biochemistry. These values were within the normal range for this species. Arterial hemoglobin oxygen saturation (SpO2) and heart rate (HR) were monitored continuously in addition to other anesthesia monitoring procedures (body temperature, respiratory rate [RR], capillary refill time, blink response, pupil position, deep pain perception reflex). All dogs maintained relatively stable SpO2 profiles during monitoring, with a mean (+/- SD) SpO2 of 92% +/- 5.4%. All other physiological variables (HR, RR, body temperature, blood pressure) were within normal limits. Following each procedure, normal behavior was noted in all dogs. All the dogs were reunited into the pack at completion of their anesthetic procedures. An injectable medetomidine-ketamine-atropine combination with maintenance by gaseous isoflurane and oxygen provides an inexpensive, reliable anesthetic for captive African wild dogs.
Keyword African Wild Dog
Ketamine Hydrochloride
Lycaon Pictus
Medetomidine Hydrochloride
Hydrochloride Combination
Veterinary Sciences
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Agriculture and Food Sciences
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Created: Wed, 15 Aug 2007, 08:25:26 EST