A review of the potential role of tumour-promoting compounds produced by Lyngbya majuscula in marine turtle fibropapillomatosis

Arthur, K. E., Shaw, G. R., Limpus, J. and Udy, J. W. (2006) A review of the potential role of tumour-promoting compounds produced by Lyngbya majuscula in marine turtle fibropapillomatosis. African Journal Of Marine Science, 28 2: 441-446.


Author Arthur, K. E.
Shaw, G. R.
Limpus, J.
Udy, J. W.
Title A review of the potential role of tumour-promoting compounds produced by Lyngbya majuscula in marine turtle fibropapillomatosis
Journal name African Journal Of Marine Science   Check publisher's open access policy
ISSN 1814-232X
1814-2338
Publication date 2006-09
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2989/18142320609504194
Volume 28
Issue 2
Start page 441
End page 446
Total pages 6
Editor Stan C. Pillar
Place of publication Grahamstown, South Africa
Publisher Nationall Inquiry Services Centre
Collection year 2006
Language eng
Subject 270702 Marine and Estuarine Ecology (incl. Marine Ichthyology)
770300 Marine Environment
Abstract Harmful algal blooms (HABs) have increased in abundance and severity in recent decades. Whereas the implications for human impacts and intoxication resulting from blooms have been extensively studied, the ecological implications of these microalgae are less well understood. Many HAB species produce biologically active, secondary metabolites and the fate of these toxins through the foodweb is generally not well understood unless it culminates in extensive fish mortalities or human poisonings. This review focusses on one HAB species, the cyanobacterium Lyngbya majuscula, and presents a hypothetical role for its involvement in fibro-papillornatosis (FP), a neoplastic disease of marine turtles. FP is expressed as benign tumours that grow both internally and externally on marine turtles, preventing vision, movement and organ function. The aetiology of FP is currently not conclusively understood, but virus material has been associated with tumours and previous studies have suggested a role for naturally produced tumour promoters. In this review, we present a hypothesis regarding the involvement of L. majuscula in FP, either through direct intoxication and action of tumour-promoting compounds or indirectly by causing seagrass loss and compromised immune function, thus leaving the turtles more susceptible to disease.
Keyword Marine & Freshwater Biology
Chelonia Mydas
Debromoaplysiatoxin
Dietary Exposure
Fibropapillomatosis
Lyngbyatoxin A
Tumour Promoter
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes SPECIAL ISSUE: Harmful Algae 2004

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
School of Civil Engineering Publications
2007 Higher Education Research Data Collection
 
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