A pragmatic 2 × 2 × 2 factorial cluster randomized controlled trial of educational outreach visiting and case conferencing in palliative care—methodology of the Palliative Care Trial [ISRCTN 81117481]

Abernethy, Amy P., Currow, David C., Hunt, Roger, Williams, Helena, Roder-Allen, Gerda, Rowett, Debra, Shelby-James, Tania, Esterman, Adrian, May, Frank and Phillips, Paddy A. (2006) A pragmatic 2 × 2 × 2 factorial cluster randomized controlled trial of educational outreach visiting and case conferencing in palliative care—methodology of the Palliative Care Trial [ISRCTN 81117481]. Contemporary Clinical Trials, 27 1: 83-100.


Author Abernethy, Amy P.
Currow, David C.
Hunt, Roger
Williams, Helena
Roder-Allen, Gerda
Rowett, Debra
Shelby-James, Tania
Esterman, Adrian
May, Frank
Phillips, Paddy A.
Title A pragmatic 2 × 2 × 2 factorial cluster randomized controlled trial of educational outreach visiting and case conferencing in palliative care—methodology of the Palliative Care Trial [ISRCTN 81117481]
Journal name Contemporary Clinical Trials   Check publisher's open access policy
ISSN 1551-7144
1559-2030
Publication date 2006-02
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.cct.2005.09.006
Volume 27
Issue 1
Start page 83
End page 100
Total pages 18
Editor Kathleen Drennan
Place of publication Philadelphia, PA, United States
Publisher Elsevier Science
Collection year 2006
Language eng
Subject 320599 Pharmacology not elsewhere classified
730306 Evaluation of health outcomes
Abstract The demand for palliative care is increasing, yet there are few data on the best models of care nor well-validated interventions that translate current evidence into clinical practice. Supporting multidisciplinary patient-centered palliative care while successfully conducting a large clinical trial is a challenge. The Palliative Care Trial (PCT) is a pragmatic 2 x 2 x 2 factorial cluster randomized controlled trial that tests the ability of educational outreach visiting and case conferencing to improve patient-based outcomes such as performance status and pain intensity. Four hundred sixty-one consenting patients and their general practitioners (GPs) were randomized to the following: (1) GP educational outreach visiting versus usual care, (2) Structured patient and caregiver educational outreach visiting versus usual care and (3) A coordinated palliative care model of case conferencing versus the standard model of palliative care in Adelaide, South Australia (3:1 randomization). Main outcome measures included patient functional status over time, pain intensity, and resource utilization. Participants were followed longitudinally until death or November 30, 2004. The interventions are aimed at translating current evidence into clinical practice and there was particular attention in the trial's design to addressing common pitfalls for clinical studies in palliative care. Given the need for evidence about optimal interventions and service delivery models that improve the care of people with life-limiting illness, the results of this rigorous, high quality clinical trial will inform practice. Initial results are expected in mid 2005. (c) 2005 Elsevier Inc. All rights reserved.
Keyword Palliative Care
Health Services Research
Adult Education
Clinical Trials Methodology
Pain Management
Medicine, Research & Experimental
Pharmacology & Pharmacy
Quality-of-life
Controlled Clinical-trial
Cancer Pain Management
Patient Education
Decision-making
Home-care
Interventions
Improve
Program
Strategies
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
2007 Higher Education Research Data Collection
School of Pharmacy Publications
 
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