A linkage study of academic skills defined by the Queensland Core Skills Test

Wainwright, Mark A., Wright, Margaret J., Luciano, Michelle, Montgomery, Grant W., Geffen, Gina M. and Martin, Nicholas G. (2006) A linkage study of academic skills defined by the Queensland Core Skills Test. Behavior Genetics, 36 1: 56-64.


Author Wainwright, Mark A.
Wright, Margaret J.
Luciano, Michelle
Montgomery, Grant W.
Geffen, Gina M.
Martin, Nicholas G.
Title A linkage study of academic skills defined by the Queensland Core Skills Test
Journal name Behavior Genetics   Check publisher's open access policy
ISSN 0001-8244
1573-3297
Publication date 2006-01
Sub-type Article (original research)
DOI 10.1007/s10519-005-9013-z
Volume 36
Issue 1
Start page 56
End page 64
Total pages 9
Editor J. K. Hewitt
Place of publication New York, United States
Publisher Springer
Collection year 2006
Language eng
Subject C1
389999 Other Behavioural and Cognitive Sciences
730299 Public health not elsewhere classified
329999 Medical and Health Sciences not elsewhere classified
730301 Health education and promotion
Abstract This study used genome-wide linkage analysis to detect Quantitative Trait Loci (QTLs) implicated in variation in general academic achievement as measured by the Queensland Core Skills Test (QCST) (Queensland Studies Authority, 2004). Data from 210 families were analysed. While no empirically derived significant or suggestive peaks for general academic achievement were indicated a peak on chromosome 2 was observed in a region where Posthuma et al. (2005) reported significant linkage for Performance IQ (PIQ) and suggestive linkage for Full Scale IQ (FSIQ), and Luciano et al. (this issue) observed significant linkage for PIQ and word reading. A peak on chromosome 18 was also observed approximately 20 cM removed from a region recently implicated in reading achievement. In addition, on chromosomes 2 and 18 peaks for a number of specific academic skills, two of which were suggestive, coincided with the general academic achievement peaks. The findings suggest that variation in general academic achievement is influenced by genes on chromosome 2 which have broad influence on a variety of cognitive abilities.
Keyword Academic achievement
Cognitive abilities
Psychology, Multidisciplinary
Genome-wide linkage
Twins
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

 
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