Layered double hydroxide nanomaterials as potential cellular drug delivery agents

Xu, Z. P. and Lu, G. Q. (2006) Layered double hydroxide nanomaterials as potential cellular drug delivery agents. Pure and Applied Chemistry, 78 9: 1771-1779. doi:10.1351/pac200678091771


Author Xu, Z. P.
Lu, G. Q.
Title Layered double hydroxide nanomaterials as potential cellular drug delivery agents
Journal name Pure and Applied Chemistry   Check publisher's open access policy
ISSN 0033-4545
1365-3075
Publication date 2006-01-01
Sub-type Article (original research)
DOI 10.1351/pac200678091771
Open Access Status Not Open Access
Volume 78
Issue 9
Start page 1771
End page 1779
Total pages 9
Editor Bernardo J. Harold
James R. Bull
John W. Lorimer
Place of publication Berlin, Germany
Publisher Walter de Gruyter GmbH
Collection year 2006
Language eng
Abstract This paper briefly reviews the recent progress in using layered double hydroxide (LDH) nanomaterials as cellular delivery agents. The advantages of LDHs as cellular delivery agents are summarized, and the processes of interaction/de-intercalation of anionic drugs (genes) into/from LDH nanoparticles are discussed. Then the cellular delivery of LDH-drug (gene) nanohybrids and subsequent intracellular processes are presumably proposed. At the end, some challenges and remarks for efficient delivery of drugs (genes) via LDH nanoparticles are provided to the best of our knowledge.
Keyword Layered Double Hydroxide (ldh)
Hydrotalcite
Drug Delivery
Gene Therapy
Endocytosis
Endosome Escape
Silica-nanoparticles
Controlled-release
Nonviral Vectors
Gene-therapy
In-vitro
Intercalation
Behavior
System
Dna
Nanobiohybrids
Chemistry, Multidisciplinary
Q-Index Code C1

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 73 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 88 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 15 Aug 2007, 08:00:49 EST