The impact of modest prematurity on visual function at age 6 years - Findings from a population-based study

Robaei, Dana, Kifley, Annette, Gole, Glen A. and Mitchell, Paul (2006) The impact of modest prematurity on visual function at age 6 years - Findings from a population-based study. Archives of Ophthalmology, 124 6: 871-877. doi:10.1001/archopht.124.6.871


Author Robaei, Dana
Kifley, Annette
Gole, Glen A.
Mitchell, Paul
Title The impact of modest prematurity on visual function at age 6 years - Findings from a population-based study
Journal name Archives of Ophthalmology   Check publisher's open access policy
ISSN 0003-9550
Publication date 2006
Sub-type Article (original research)
DOI 10.1001/archopht.124.6.871
Volume 124
Issue 6
Start page 871
End page 877
Total pages 7
Editor D. M. Albert
M. F. Goldberg
Place of publication Chicago, U.S.A.
Publisher American Medical Association
Collection year 2006
Language eng
Subject C1
321016 Opthalmology and Vision Science
730204 Child health
Formatted abstract
Objective To determine the effects of modest low birth weight and prematurity on visual function of children predominantly aged 6 years.

Methods Children with a birth weight of 1500 to 2499 g were considered exposed to a modest low birth weight (n = 82) and were compared with children with a birth weight of 2500 g or more (n = 1386). Exposure to modest prematurity, 32 to 36 weeks' gestation (n = 115), was similarly analyzed and compared with birth at term, 37 or more weeks' gestation (n = 1446). Logarithm of the minimum angle of resolution visual acuity was measured in both eyes. Cycloplegic autorefraction (cyclopentolate), cover testing, and dilated fundus examinations were performed.

Results A modest low birth weight increased the risk of amblyopia (relative risk [RR], 5.1; 95% confidence interval [CI], 2.2-12.0), strabismus (RR, 3.7; 95% CI, 1.5-9.1), and anisometropia (RR, 3.7; 95% CI, 1.2-11.1), together with an increased risk of uncorrected visual acuity in the lowest quartile (RR, 1.7; 95% CI, 1.3-2.2). Modest prematurity increased the risk of amblyopia (RR, 4.5; 95% CI, 1.9-10.6), strabismus (RR, 2.6; 95% CI, 1.1-6.0), and uncorrected visual acuity in the lowest quartile (RR, 1.5; 95% CI, 1.1-2.0).

Conclusion Modest degrees of low birth weight and prematurity may be associated with increased ophthalmic morbidity at age 6 years.
Keyword Ophthalmology
Low-birth-weight
32 Weeks Gestation
Term-follow-up
Children Born
Ophthalmic Changes
Ultrasound Oculometry
Australian Children
Refractive Errors
Preterm Infants
Retinopathy
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2007 Higher Education Research Data Collection
School of Medicine Publications
 
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Created: Wed, 15 Aug 2007, 07:55:46 EST