The effect of admission physiological variables on 30 day outcome after stroke

Wong, Andrew A., Davis, James P., Schluter, Philip J., Henderson, Robert D., O'Sullivan, John D. and Read, Stephen J. (2005) The effect of admission physiological variables on 30 day outcome after stroke. Journal of Clinical Neuroscience, 12 8: 905-910. doi:10.1016/j.jocn.2004.11.012

Author Wong, Andrew A.
Davis, James P.
Schluter, Philip J.
Henderson, Robert D.
O'Sullivan, John D.
Read, Stephen J.
Title The effect of admission physiological variables on 30 day outcome after stroke
Journal name Journal of Clinical Neuroscience   Check publisher's open access policy
ISSN 0967-5868
Publication date 2005
Sub-type Article (original research)
DOI 10.1016/j.jocn.2004.11.012
Volume 12
Issue 8
Start page 905
End page 910
Total pages 6
Editor G. Griffith
Place of publication Kidlington, United Kingdom
Publisher Churchill Livingstone
Collection year 2005
Language eng
Subject C1
1117 Public Health and Health Services
Abstract Introduction. Potentially modifiable physiological variables may influence stroke prognosis but their independence from modifiable factors remains unclear. Methods. Admission physiological measures (blood pressure, heart rate, temperature and blood glucose) and other unmodifiable factors were recorded from patients presenting within 48 hours of stroke. These variables were compared with the outcomes of death and death or dependency at 30 days in multivariate statistical models. Results. In the 186 patients included in the study, age, atrial fibrillation and the National Institutes of Health Stroke Score were identified as unmodifiable factors independently associated with death and death or dependency. After adjusting for these factors, none of the physiological variables were independently associated with death, while only diastolic blood pressure (DBP) >= 90 mmHg was associated with death or dependency at 30 days (p = 0.02). Conclusions. Except for elevated DBP, we found no independent associations between admission physiology and outcome at 30 days in an unselected stroke cohort. Future studies should look for associations in subgroups, or by analysing serial changes in physiology during the early post-stroke period.
Keyword Clinical Neurology
Acute Ischemic-stroke
Blood-pressure Levels
Intracerebral Hemorrhage
Cerebral Infarction
Prognostic Value
1st-ever Stroke
Q-Index Code C1
Institutional Status UQ

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Created: Wed, 15 Aug 2007, 07:44:02 EST