Analysis of cardiac ventricular wall motion based on a three-dimensional electromechanical biventricular model

Xia, Ling, Huo, Meimei M., Wei, Qing, Liu, Feng and Crozier, Stuart (2005) Analysis of cardiac ventricular wall motion based on a three-dimensional electromechanical biventricular model. Physics in Medicine and Biology, 50 8: 1901-1917.


Author Xia, Ling
Huo, Meimei M.
Wei, Qing
Liu, Feng
Crozier, Stuart
Title Analysis of cardiac ventricular wall motion based on a three-dimensional electromechanical biventricular model
Journal name Physics in Medicine and Biology  (ERA 2012 Listed)    (ERA 2010 Rank A)   Check publisher's open access policy
Publication date 2005-04-21
Sub-type Article
DOI 10.1088/0031-9155/50/8/018
Volume number 50
Issue number 8
ISSN 0031-9155
Start page 1901
End page 1917
Total pages 17
Editor S. Webb
Place of publication Bristol
Publisher IOP Publishing Ltd
Collection year 2005
Language eng
Subject C1
090399 Biomedical Engineering not elsewhere classified
Abstract This paper describes a biventricular model, which couples the electrical and mechanical properties of the heart, and computer simulations of ventricular wall motion and deformation by means of a biventricular model. In the constructed electromechanical model, the mechanical analysis was based on composite material theory and the finite-element method; the propagation of electrical excitation was simulated using an electrical heart model, and the resulting active forces were used to calculate ventricular wall motion. Regional deformation and Lagrangian strain tensors were calculated during the systole phase. Displacements, minimum principal strains and torsion angle were used to describe the motion of the two ventricles. The simulations showed that during the period of systole, (1) the right ventricular free wall moves towards the septum, and at the same time, the base and middle of the free wall move towards the apex, which reduces the volume of the right ventricle; the minimum principle strain (E3) is largest at the apex, then at the middle of the free wall and its direction is in the approximate direction of the epicardial muscle fibres; (2) the base and middle of the left ventricular free wall move towards the apex and the apex remains almost static; the torsion angle is largest at the apex; the minimum principle strain E3 is largest at the apex and its direction on the surface of the middle wall of the left ventricle is roughly in the fibre orientation. These results are in good accordance with results obtained from MR tagging images reported in the literature. This study suggests that such an electromechanical biventricular model has the potential to be used to assess the mechanical function of the two ventricles, and also could improve the accuracy ECG simulation when it is used in heart torso model-based body surface potential simulation studies.
Keyword Engineering, Biomedical
Radiology, Nuclear Medicine & Medical Imaging
Rat Left-ventricle
Spatial Modulation
3-dimensional Motion
Mathematical-model
Tagged Mri
Heart
Deformation
Mechanics
Simulation
Stress
Q-Index Code C1

 
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