Treatment of acute vivax malaria with tafenoquine

Nasveld, Peter and Kitchener, Scott (2005) Treatment of acute vivax malaria with tafenoquine. Transactions of The Royal Society of Tropical Medicine And Hygiene, 99 1: 2-5. doi:10.1016/j.trstmh.2004.01.013

Author Nasveld, Peter
Kitchener, Scott
Title Treatment of acute vivax malaria with tafenoquine
Journal name Transactions of The Royal Society of Tropical Medicine And Hygiene   Check publisher's open access policy
ISSN 0035-9203
Publication date 2005-01
Sub-type Article (original research)
DOI 10.1016/j.trstmh.2004.01.013
Volume 99
Issue 1
Start page 2
End page 5
Total pages 4
Editor Harold Townson
Place of publication United Kingdom
Publisher Elsevier Ltd
Collection year 2005
Language eng
Subject CX
321208 Primary Health Care
730299 Public health not elsewhere classified
Abstract Tafenoquine is an 8-aminoquiniline related to primaquine with preclinical activity against a range of malaria species. We treated two acute cases of vivax malaria with tafenoquine (800 mg over three days) atone, instead of conventional chloroquine (1500 mg over three days) and primaquine (420 mg over 14 days). In addition to the convenience of this regimen, the rapid parasite clearances observed, coupled with a good clinical response and lack of recrudescence or relapse, indicate that further investigation of tafenoquine in the treatment of vivax malaria is warranted. (C) 2004 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
Keyword Public, Environmental & Occupational Health
Tropical Medicine
Plasmodium Vivax
Papua New Guinea
Chloroquine-resistant Strain
Wr 238605
Q-Index Code CX

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 59 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 15 Aug 2007, 06:57:31 EST