Nutritional status and energy expenditure in children pre-bone-marrow-transplant

White, M., Murphy, A.J., Hastings, Y., Shergold, J., Young, J., Montgomery, C., Davies, P. S. W. and Lockwood, L. (2005) Nutritional status and energy expenditure in children pre-bone-marrow-transplant. Bone Marrow Transplantation, 35 8: 775-779. doi:10.1038/sj.bmt.1704891


Author White, M.
Murphy, A.J.
Hastings, Y.
Shergold, J.
Young, J.
Montgomery, C.
Davies, P. S. W.
Lockwood, L.
Title Nutritional status and energy expenditure in children pre-bone-marrow-transplant
Journal name Bone Marrow Transplantation   Check publisher's open access policy
ISSN 0268-3369
Publication date 2005
Sub-type Article (original research)
DOI 10.1038/sj.bmt.1704891
Volume 35
Issue 8
Start page 775
End page 779
Total pages 5
Editor J. M. Goldman
Place of publication London, U.K.
Publisher Nature Publishing Group
Collection year 2005
Language eng
Subject C1
321019 Paediatrics
730204 Child health
11 Medical and Health Sciences
1111 Nutrition and Dietetics
1103 Clinical Sciences
Abstract The aims of this study were to establish the nutritional status of children pre- BMT and to determine whether predictive methods of assessing nutritional status and resting energy expenditure ( REE) are accurate in this population. We analysed the body cell mass ( BCM) ( n = 26) and REE ( n = 24) in children undergoing BMT. BCM was adjusted for height ( BCM/ HTp) and expressed as a Z score to represent nutritional status. To determine whether body mass index ( BMI) was indicative of nutritional status in children undergoing BMT, BMI Z scores were compared to the reference method of BCM/ HTp Z scores. Schofield predictive equations of basal metabolic rate ( BMR) were compared to measured REE to evaluate the accuracy of the predictive equations. The mean BCM/ HTp Z score for the subject population was -1.09 +/- 1.28. There was no significant relationship between BCM/ HTp Z score and BMI Z score ( r = 0.34; P > 0.05); however there was minimal difference between measured REE and predicted BMR ( bias = -11 +/- 149 kcal/ day). The results of this study demonstrate that children undergoing BMT may have suboptimal nutritional status and that BMI is not an accurate indication of nutritional status in this population. However, Schofield equations were found to be suitable for representing REE in children pre- BMT.
Keyword Children
Nutritional Status
Resting Energy Expenditure
Body Cell Mass
Oncology
Hematology
Immunology
Transplantation
Total Parenteral-nutrition
Support
Recipients
Index
Biophysics
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
2006 Higher Education Research Data Collection
School of Medicine Publications
 
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Created: Wed, 15 Aug 2007, 06:18:26 EST