Genetic and economic analysis of a targeted marker-assisted wheat breeding strategy

Kuchel, Haydn, Ye, Guoyou, Fox, Rebecca and Jefferies, Stephen (2005) Genetic and economic analysis of a targeted marker-assisted wheat breeding strategy. Molecular Breeding, 16 1: 67-78. doi:10.1007/s11032-005-4785-7

Author Kuchel, Haydn
Ye, Guoyou
Fox, Rebecca
Jefferies, Stephen
Title Genetic and economic analysis of a targeted marker-assisted wheat breeding strategy
Journal name Molecular Breeding   Check publisher's open access policy
ISSN 1380-3743
Publication date 2005-08
Sub-type Article (original research)
DOI 10.1007/s11032-005-4785-7
Volume 16
Issue 1
Start page 67
End page 78
Total pages 12
Place of publication Dordrecht, Germany
Publisher Springer
Collection year 2005
Language eng
Subject C1
270207 Quantitative Genetics
620101 Wheat
Abstract The advent of molecular markers as a tool to aid selection has provided plant breeders with the opportunity to rapidly deliver superior genetic solutions to problems in agricultural production systems. However, a major constraint to the implementation of marker-assisted selection (MAS) in pragmatic breeding programs in the past has been the perceived high relative cost of MAS compared to conventional phenotypic selection. In this paper, computer simulation was used to design a genetically effective and economically efficient marker-assisted breeding strategy aimed at a specific outcome. Under investigation was a strategy involving the integration of both restricted backcrossing and doubled haploid (DH) technology. The point at which molecular markers are applied in a selection strategy can be critical to the effectiveness and cost efficiency of that strategy. The application of molecular markers was considered at three phases in the strategy: allele enrichment in the BC1F1 population, gene selection at the haploid stage and the selection for recurrent parent background of DHs prior to field testing. Overall, incorporating MAS at all three stages was the most effective, in terms of delivering a high frequency of desired outcomes and at combining the selected favourable rust resistance, end use quality and grain yield alleles. However, when costs were included in the model the combination of MAS at the BC1F1 and haploid stage was identified as the optimal strategy. A detailed economic analysis showed that incorporation of marker selection at these two stages not only increased genetic gain over the phenotypic alternative but actually reduced the over all cost by 40%.
Keyword economics
marker-assisted selection
plant breeding
Triticum aestivum
Bread Wheat
Rust Resistance
Dna Markers
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2006 Higher Education Research Data Collection
School of Agriculture and Food Sciences
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 57 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 60 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 15 Aug 2007, 05:54:49 EST