The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty: Enoxaparin versus aspirin

Keays, A. C., Mason, M., Keays, S. L. and Newcombe, P. A. (2003) The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty: Enoxaparin versus aspirin. Journal of Arthroplasty, 18 2: 180-185. doi:10.1054/arth.2003.50024


Author Keays, A. C.
Mason, M.
Keays, S. L.
Newcombe, P. A.
Title The effect of anticoagulation on the restoration of range of motion after total knee arthroplasty: Enoxaparin versus aspirin
Journal name Journal of Arthroplasty   Check publisher's open access policy
ISSN 0883-5403
Publication date 2003-02
Sub-type Article (original research)
DOI 10.1054/arth.2003.50024
Volume 18
Issue 2
Start page 180
End page 185
Total pages 6
Editor Dr G. Bentley
Dr Richard Rothman
Place of publication United States
Publisher Churchill Livingstone
Collection year 2004
Language eng
Subject C1
380101 Sensory Processes, Perception and Performance
730306 Evaluation of health outcomes
Abstract Anticoagulation used for thromboembolic prophylaxis following total knee arthroplasty (TKA) could interfere with movement. This study compares the effect of 2 anticoagulants, enoxaparin and aspirin, on restoration of range of motion (ROM) after TKA. Two groups of 75 consecutive patients, matched for age, arthritic severity, and preoperative ROM, underwent TKA. Flexion and extension milestone measures were recorded daily. Results show a highly statistically significant difference (P<.001) between the 2 groups when comparing the days on which these milestones were achieved. Group 1 (enoxaparin) reached 90&DEG;, 100&DEG; and 110&DEG; of flexion in 8.4, 10.4, and 12.4 days, respectively. Group 2 (aspirin) reached the same goals in 6.8, 8.5, and 10.6 days, respectively. At 15 months alter surgery, no statistically significant difference in flexion was seen between the groups (122&DEG; vs 121&DEG;). Enoxaparin delayed the return of early but not long-term flexion after TKA.
Keyword Thromboembolism
Knee Arthroplasty
Flexion
Extension
Enoxaparin
Aspirin
Orthopedics
Prophylaxis
Thrombosis
Q-Index Code C1

 
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Created: Wed, 15 Aug 2007, 04:56:46 EST