Metabolites from marine sponges of the genus Plakortis

Rahm, Fredirik, Hayes, Patricia Y. and Kitching, William (2004) Metabolites from marine sponges of the genus Plakortis. Heterocycles, 64 1: 523-575. doi:10.3987/REV-04-SR(P)1


Author Rahm, Fredirik
Hayes, Patricia Y.
Kitching, William
Title Metabolites from marine sponges of the genus Plakortis
Journal name Heterocycles   Check publisher's open access policy
ISSN 0385-5414
Publication date 2004-12
Sub-type Critical review of research, literature review, critical commentary
DOI 10.3987/REV-04-SR(P)1
Volume 64
Issue 1
Start page 523
End page 575
Total pages 53
Place of publication Japan
Publisher Japan Institute of Heterocyclic Chemistry
Collection year 2004
Language eng
Subject C1
250302 Biological and Medical Chemistry
780103 Chemical sciences
Formatted abstract
Metabolites from the Plakortis genus of sponges are reviewed, with major focus on P. halichondrioides, P.simplex, P. angulospiculatus, P. lita, P. nigra, P. quasiamphiaster, P. zygompha, and the closely related Plakinastrella onkodes. The structures, stereochemistry, pharmacological activity and selected syntheses of these metabolites are discussed. Peroxy containing, polyketide derived metabolites constitute a prevalent class of biologically potent metabolites from Plakortis species.
Keyword Chemistry, Organic
Cyclic Polyketide Peroxides
Fatty-acid Derivatives
Elenic Acid
Absolute Stereochemistry
Plakinastrella-onkodes
Topoisomerase-ii
Cytotoxic Metabolites
Biological Evaluation
Caribbean Sponges
Natural-products
Q-Index Code C1

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
2005 Higher Education Research Data Collection
School of Chemistry and Molecular Biosciences
 
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Created: Wed, 15 Aug 2007, 04:26:31 EST