The gender differences in health effects of environmental cadmium exposure and potential mechanisms

Nishijo, Muneko, Satarug, Soisungwan, Honda, Ryumon, Tsuritani, Ikiko and Aoshima, Keiko (2004) The gender differences in health effects of environmental cadmium exposure and potential mechanisms. Molecular And Cellular Biochemistry, 255 1-2: 87-92. doi:10.1023/B:MCBI.0000007264.37170.39


Author Nishijo, Muneko
Satarug, Soisungwan
Honda, Ryumon
Tsuritani, Ikiko
Aoshima, Keiko
Title The gender differences in health effects of environmental cadmium exposure and potential mechanisms
Journal name Molecular And Cellular Biochemistry   Check publisher's open access policy
ISSN 0300-8177
Publication date 2004-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1023/B:MCBI.0000007264.37170.39
Volume 255
Issue 1-2
Start page 87
End page 92
Total pages 6
Place of publication The Hague, The Netherlands
Publisher Kluwer Academic Publishers
Collection year 2004
Language eng
Subject C1
321299 Public Health and Health Services not elsewhere classified
730210 Environmental health
Abstract On a viewpoint of gender differences in Cd body burden and its health effects, we reviewed the population- based research including our own which conducted in Japan, Thailand, Australia, Poland, Belgium and Sweden to assess health effects of human exposure to environmental cadmium and their potential mechanisms. As a result, six risk factors in Cd health effects in women have been identified; ( 1) more serious type of renal tubular dysfunction, ( 2) difference in calcium metabolism and its regulatory hormones, ( 3) kidney sensitivity; difference in P450 phenotype, ( 4) pregnancy, ( 5) body iron store status, and ( 6) genetic factors. Further studies of Cd toxicity targeted to women would now appear necessary.
Keyword Cell Biology
Cadmium
Gender Difference
Renal Tubular Dysfunction
Kidney Sensitivity
Bone Injury
Kidney Cortex
Population
Absorption
Expression
Liver
Iron
Q-Index Code C1

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: 2005 Higher Education Research Data Collection
School of Public Health Publications
 
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Created: Wed, 15 Aug 2007, 03:59:42 EST