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Medicinal herbal extracts - renal friend or foe? Part one: The toxicities of medicinal herbs

Wojcikowski, Ken, Johnson, David W. and Gobe, Glenda (2004-10) Medicinal herbal extracts - renal friend or foe? Part one: The toxicities of medicinal herbs. Nephrology, 9 5: 313-318.


Author(s) Wojcikowski, Ken
Johnson, David W.
Gobe, Glenda
Title Medicinal herbal extracts - renal friend or foe? Part one: The toxicities of medicinal herbs
Journal name Nephrology
Publication date 2004-10
Volume number 9
Issue number 5
ISSN 1320-5358
Start page 313
End page 318
Total pages 6
Editor(s) David Harris
Place of publication Carlton, Vic.
Publisher Blackwell Science
Collection year 2004
Language eng
Subject CX
730118 Organs, diseases and abnormal conditions not elsewhere classified
110312 Nephrology and Urology
Abstract In recent years, an increasing percentage of people from industrialized countries have been using complementary and alternative medicines (CAM). This, combined with numerous warnings regarding the potential toxicity of these therapies, suggests the need for practitioners to keep abreast of the reported incidence of renal toxicity caused by the ingestion of medicinal herbs. The goal of the present two-part series, on the toxic or beneficial effects of medicinal herbs on renal health, is to provide practitioners with a summary of the most recent information as well as the means by which evidence for benefit or toxicity has been found. In this first article, we explore in vivo evidence of toxicity. Included are nephrotoxicity from aristolochic acid and other components within herbs, herb-drug interactions resulting in adverse renal effects, and renal toxicity from contaminants within the extracts. The review aims to provide a guide to encourage future toxicity studies and rigorous clinical trials.
Keyword(s) Urology & Nephrology
Aristolochic Acid Nephropathy
Chinese Herbs Nephropathy
Complementary And Alternative Medicine
Herbal Medicine
Toxicity
St-johns-wort
Chinese Herbs
Aristolochic Acid
Heavy-metals
Nephropathy
Failure
Fibrosis
Cyclosporine
Supplements
Ochratoxin
Additional Notes This document is a journal review.
 
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http://dx.doi.org/10.1111/j.1440-1797.2004.00310.x  
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http://www3.interscience.wiley.com/journal/118522537/home  
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