Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis

Anderson, Jonathan P., Badruzsaufari, Ellet, Schenk, Peer M., Manners, John M., Desmond, Olivia J., Ehlert, Christina, Maclean, Donald J., Ebert, Paul R. and Kazan, Kemal (2004) Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis. Plant Cell, 16 12: 3460-3479.


Author Anderson, Jonathan P.
Badruzsaufari, Ellet
Schenk, Peer M.
Manners, John M.
Desmond, Olivia J.
Ehlert, Christina
Maclean, Donald J.
Ebert, Paul R.
Kazan, Kemal
Title Antagonistic interaction between abscisic acid and jasmonate-ethylene signaling pathways modulates defense gene expression and disease resistance in Arabidopsis
Journal name Plant Cell   Check publisher's open access policy
ISSN 1040-4651
Publication date 2004-12
Sub-type Article (original research)
DOI 10.1105/tpc.104.025833
Volume 16
Issue 12
Start page 3460
End page 3479
Total pages 20
Editor Quatrano, R. S.
Place of publication Rockville
Publisher American Society of Plant Biologists
Collection year 2004
Language eng
Subject C1
270403 Plant Pathology
780105 Biological sciences
Abstract The plant hormones abscisic acid (ABA), jasmonic acid (JA), and ethylene are involved in diverse plant processes, including the regulation of gene expression during adaptive responses to abiotic and biotic stresses. Previously, ABA has been implicated in enhancing disease susceptibility in various plant species, but currently very little is known about the molecular mechanisms underlying this phenomenon. In this study, we obtained evidence that a complex interplay between ABA and JA-ethylene signaling pathways regulate plant defense gene expression and disease resistance. First, we showed that exogenous ABA suppressed both basal and JA-ethylene-activated transcription from defense genes. By contrast, ABA deficiency as conditioned by the mutations in the ABA1 and ABA2 genes, which encode enzymes involved in ABA biosynthesis, resulted in upregulation of basal and induced transcription from JA-ethylene responsive defense genes. Second, we found that disruption of AtMYC2 (allelic to JASMONATE INSENSITIVE1 [JIN1]), encoding a basic helix-loop-helix Leu zipper transcription factor, which is a positive regulator of ABA signaling, results in elevated levels of basal and activated transcription from JA-ethylene responsive defense genes. Furthermore, the jin1/myc2 and aba2-1 mutants showed increased resistance to the necrotrophic fungal pathogen Fusarium oxysporum. Finally, using ethylene and ABA signaling mutants, we showed that interaction between ABA and ethylene signaling is mutually antagonistic in vegetative tissues. Collectively, our results indicate that the antagonistic interactions between multiple components of ABA and the JA-ethylene signaling pathways modulate defense and stress responsive gene expression in response to biotic and abiotic stresses.
Keyword Biochemistry & Molecular Biology
Plant Sciences
Cell Biology
Protein Phosphatase 2c
Fungus Fusarium-oxysporum
Vascular Wilt Fungus
Salicylic-acid
Transcription Factor
Plant Defense
Cross-talk
Microarray Analysis
Methyl-jasmonate
Insensitive Mutants
Q-Index Code C1

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 328 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 350 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Access Statistics: 149 Abstract Views  -  Detailed Statistics
Created: Wed, 15 Aug 2007, 03:37:25 EST