The use of air displacement plethysmography in children and adolescents with cystic fibrosis

Murphy, A. J., Buntain, H. M., Wong, J. C. H., Greer, R. M., Wainwright, C. E. and Davies, P. S. W (2004) The use of air displacement plethysmography in children and adolescents with cystic fibrosis. European Journal of Clinical Nutrition, 58 7: 985-989. doi:10.1038/sj.ejcn.1601919

Author Murphy, A. J.
Buntain, H. M.
Wong, J. C. H.
Greer, R. M.
Wainwright, C. E.
Davies, P. S. W
Title The use of air displacement plethysmography in children and adolescents with cystic fibrosis
Journal name European Journal of Clinical Nutrition   Check publisher's open access policy
ISSN 0954-3007
Publication date 2004-07
Sub-type Article (original research)
DOI 10.1038/sj.ejcn.1601919
Volume 58
Issue 7
Start page 985
End page 989
Total pages 5
Editor J. C. Seidell
Place of publication London, U.K.
Publisher Nature Publishing Group
Collection year 2004
Language eng
Subject C1
321019 Paediatrics
730204 Child health
110203 Respiratory Diseases
11 Medical and Health Sciences
1111 Nutrition and Dietetics
Formatted abstract
Objectives: The purpose of this paper was to evaluate the use of air displacement plethysmography ( ADP) in children and adolescents with cystic fibrosis (CF). Specifically, the primary aim of this study was to compare estimates of fat-free mass (FFM) measured from ADP and dual energy X-ray absorptiometry ( DEXA) in children and adolescents with CF. The secondary aim was to compare the effect of using predicted thoracic gas volume (VTG) and measured VTG for the calculation of FFM by ADP in this population.
Methods: Cross-sectional FFM measurements were taken using ADP and DEXA in 52 children and adolescents with CF, ranging in age from 6.3 to 16.6 y.
Results: Bland-Altman analysis showed that ADP values of FFM were on average 0.59 kg higher than DEXA values (95% limits of agreement = 3.61 to -2.43 kg); however this difference was not significant. There was no significant correlation (r= -0.26, P=0.07) between the mean FFM and difference in FFM between ADP and DEXA. Using either predicted or measured VTG did not significantly affect FFM estimates in individuals with CF who had normal lung function (bias= -0.39 ± 0.86 kg; r= -0.02, P=0.93). Conclusions: ADP is an appropriate technique for use in children and adolescents with CF.
© 2004 Nature Publishing Group All rights reserved

Keyword Nutrition and dietetics
Air displacement plethysmography
Cystic Fibrosis
Fat-free mass
Dual energy X-ray absorptiometry
Body composition
Body-composition analysis
X-ray Absorptiometry
4-compartment model
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

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Created: Wed, 15 Aug 2007, 03:34:12 EST