A novel venom peptide from an endoparasitoid wasp is required for expression of polydnavirus genes in host hemocytes

Zhang, G. M., Schmidt, O. and Asgari, S. (2004) A novel venom peptide from an endoparasitoid wasp is required for expression of polydnavirus genes in host hemocytes. Journal of Biological Chemistry, 279 40: 41580-41585. doi:10.1074/jbc.M406865200


Author Zhang, G. M.
Schmidt, O.
Asgari, S.
Title A novel venom peptide from an endoparasitoid wasp is required for expression of polydnavirus genes in host hemocytes
Journal name Journal of Biological Chemistry   Check publisher's open access policy
ISSN 0021-9258
Publication date 2004
Sub-type Article (original research)
DOI 10.1074/jbc.M406865200
Volume 279
Issue 40
Start page 41580
End page 41585
Total pages 6
Editor H.Taylor
Place of publication Bethesda
Publisher American Society for Biochemistry and Molecular Biology, Inc.
Collection year 2004
Language eng
Subject C1
270100 Biochemistry and Cell Biology
780105 Biological sciences
Abstract Maternal factors introduced into host insects by endoparasitoid wasps are usually essential for successful parasitism. This includes polydnaviruses (PDVs) that are produced in the reproductive organ of female hymenopteran endoparasitoids and are injected, together with venom proteins, into the host hemocoel at oviposition. Inside the host, PDVs enter various tissue cells and hemocytes where viral genes are expressed, leading to developmental and physiological alterations in the host, including the suppression of the host immune system. Although several studies have shown that some PDVs are only effective when accompanied by venom proteins, there is no report of an active venom ingredient(s) facilitating PDV infection and/or gene expression. In this study, we describe a novel peptide (Vn1.5) isolated from Cotesia rubecula venom that is required for the expression of C. rubecula bracoviruses (CrBVs) in host hemocytes (Pieris rapae), although it is not essential for CrBV entry into host cells. The peptide consists of 14 amino acids with a molecular mass of 1598 Da. In the absence of Vn1.5 or total venom proteins, CrBV genes are not expressed in host cells and did not cause inactivation of host hemocytes.
Keyword Biochemistry & Molecular Biology
Pseudaletia-separata Walker
Apanteles-kariyai Watanabe
Manduca-sexta Larvae
Heliothis-virescens
Cotesia-rubecula
Pieris-rapae
Microplitis-croceipes
Lacanobia-oleracea
Parasitoid Wasp
Calyx Fluid
Q-Index Code C1

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 26 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 27 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Access Statistics: 52 Abstract Views  -  Detailed Statistics
Created: Wed, 15 Aug 2007, 03:07:24 EST